ARG45788
anti-IRF2BP1 antibody
anti-IRF2BP1 antibody for Flow cytometry,ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Immunoprecipitation,Western blot and Human,Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes IRF2BP1 |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | FACS, ICC/IF, IHC-P, IP, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | IRF2BP1 |
| 抗原物种 | Human |
| 抗原 | Recombinant protein containing to human IRF2BP1. |
| 偶联标记 | Un-conjugated |
| 別名 | IRF2BP1; Interferon Regulatory Factor 2 Binding Protein 1; IRF-2BP1; Probable RING-Type E3 Ubiquitin Transferase IRF2BP1; Interferon Regulatory Factor 2-Binding Protein 1; Probable E3 Ubiquitin-Protein Ligase IRF2BP1; IRF-2-Binding Protein 1; DKFZP434M154; EC 2.3.2.27 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||||||
| 实际分子量 | 72 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified |
| 缓冲液 | 0.2% Na2HPO4, 0.9% NaCl and 4% Trehalose. |
| 稳定剂 | 4% Trehalose |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # Q8IU81 Human Interferon regulatory factor 2-binding protein 1 Swiss-port # Q8R3Y8 Mouse Interferon regulatory factor 2-binding protein 1 |
|---|---|
| 基因名称 | IRF2BP1 |
| 全名 | Interferon Regulatory Factor 2 Binding Protein 1 |
| 背景介绍 | Enables transcription corepressor activity and ubiquitin protein ligase activity. Involved in protein polyubiquitination. Acts upstream of or within negative regulation of transcription by RNA polymerase II. Located in nucleoplasm. [provided by Alliance of Genome Resources, Feb 2025] |
| 生物功能 | Acts as a transcriptional corepressor in a IRF2-dependent manner; this repression is not mediated by histone deacetylase activities. May act as an E3 ligase towards JDP2, enhancing its polyubiquitination. Represses ATF2-dependent transcriptional activation. [UniProt] |
| 细胞定位 | Nucleus. [UniProt] |
| 预测分子量 | 62 kDa |
| 翻译后修饰 | Isopeptide bond; Methylation; Phosphoprotein; Ubl conjugation. [UniProt] |
检测图片 (9) Click the Picture to Zoom In
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ARG45788 anti-IRF2BP1 antibody IHC-P image
Immunohistochemistry: Rat brain stained with ARG45788 anti-IRF2BP1 antibody at 2 μg/ml dilution.
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ARG45788 anti-IRF2BP1 antibody ICC/IF image
Immunofluorescence: TPC1 stained with ARG45788 anti-IRF2BP1 antibody at 5 μg/ml dilution.
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ARG45788 anti-IRF2BP1 antibody IHC-P image
Immunohistochemistry: Mouse brain stained with ARG45788 anti-IRF2BP1 antibody at 2 μg/ml dilution.
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ARG45788 anti-IRF2BP1 antibody WB image
Western blot: 293T stained with ARG45788 anti-IRF2BP1 antibody at 0.5 μg/ml dilution.
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ARG45788 anti-IRF2BP1 antibody IP image
Immunoprecipitation: HepG2 lysate immunoprecipitated with 2 μg ARG45788 anti-IRF2BP1 antibody.
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ARG45788 anti-IRF2BP1 antibody FACS image
Flow Cytometry: HEL stained with ARG45788 anti-IRF2BP1 antibody at 1 µg/10^6 cells dilution.
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ARG45788 anti-IRF2BP1 antibody IHC-P image
Immunohistochemistry: Rat brain stained with ARG45788 anti-IRF2BP1 antibody at 2 μg/ml dilution.
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ARG45788 anti-IRF2BP1 antibody WB image
Western blot: Rat brain stained with ARG45788 anti-IRF2BP1 antibody at 0.5 μg/ml dilution.
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ARG45788 anti-IRF2BP1 antibody WB image
Western blot: Mouse brain stained with ARG45788 anti-IRF2BP1 antibody at 0.5 μg/ml dilution.
