ARG46214
anti-IQSEC2 antibody
anti-IQSEC2 antibody for Western blot,IHC-Formalin-fixed paraffin-embedded sections and Human,Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes IQSEC2 |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | IQSEC2 |
| 抗原物种 | Human |
| 抗原 | A 18 amino acid synthetic peptide within aa. 1380 - 1430 of human IQSEC2. |
| 偶联标记 | Un-conjugated |
| 別名 | IQSEC2; IQ motif and Sec7 domain 2; Brefeldin-resistant Arf-GEF 1 protein; BRAG1; MRX1 |
应用说明
| 应用建议 |
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|---|---|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| 实际分子量 | 140 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity chromatography purified |
| 缓冲液 | PBS and 0.02% Sodium azide. |
| 抗菌剂 | 0.02% Sodium azide |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -264°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # Q5DU25 Mouse IQ motif and SEC7 domain-containing protein 2 Swiss-port # Q5JU85 Human IQ motif and SEC7 domain-containing protein 2 |
|---|---|
| 基因名称 | IQSEC2 |
| 全名 | IQ motif and Sec7 domain 2 |
| 背景介绍 | This gene encodes a guanine nucleotide exchange factor for the ARF family of small GTP-binding proteins. The encoded protein is a component of the postsynaptic density at excitatory synapses, and may play a critical role in cytoskeletal and synaptic organization through the activation of selected ARF substrates including ARF1 and ARF6. Mutations in this gene have been implicated in nonsyndromic X-linked cognitive disability. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Aug 2011] |
| 生物功能 | Is a guanine nucleotide exchange factor for the ARF GTP-binding proteins. [UniProt] |
| 细胞定位 | Cytoplasm. [UniProt] |
| 预测分子量 | 104, 133, 141, 164 kDa |
| 翻译后修饰 | Phosphoprotein; Methylation. [UniProt] |
