ARG44483
anti-INTU antibody
anti-INTU antibody for Flow cytometry,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes INTU |
|---|---|
| 反应物种 | Hu |
| 应用 | FACS, IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | INTU |
| 抗原物种 | Human |
| 抗原 | Human INTU recombinant protein |
| 偶联标记 | Un-conjugated |
| 別名 | INTU; Inturned Planar Cell Polarity Protein; KIAA1284; CPLANE4; PDZD6; PDZK6; Ciliogenesis And Planar Polarity Effector Complex Subunit 4; Inturned Planar Cell Polarity Effector Homolog; PDZ Domain-Containing Protein 6; PDZ Domain Containing 6; Protein Inturned; Inturned Planar Cell Polarity Effector Homolog (Drosophila); Ciliogenesis And Planar Polarity Effector 4; SRTD20; OFD17; INT |
应用说明
| 应用建议 |
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| 应用说明 | The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified with Immunogen. |
| 缓冲液 | 0.9% NaCl, 0.2% Na2HPO4, 0.05% Sodium azide and 4% Trehalose. |
| 抗菌剂 | 0.05% Sodium azide |
| 稳定剂 | 4% Trehalose |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | INTU |
| 全名 | Inturned Planar Cell Polarity Protein |
| 背景介绍 | Involved in embryonic digit morphogenesis; roof of mouth development; and tongue morphogenesis. Located in ciliary basal body and motile cilium. Implicated in asphyxiating thoracic dystrophy and orofaciodigital syndrome XVII. |
| 生物功能 | Plays a key role in ciliogenesis and embryonic development. Regulator of cilia formation by controlling the organization of the apical actin cytoskeleton and the positioning of the basal bodies at the apical cell surface, which in turn is essential for the normal orientation of elongating ciliary microtubules. Plays a key role in definition of cell polarity via its role in ciliogenesis but not via conversion extension. Has an indirect effect on hedgehog signaling. |
| 细胞定位 | Cell projection, Cytoplasm, Cytoskeleton |
| 预测分子量 | 106 kDa |
| 翻译后修饰 | Phosphoprotein |
检测图片 (3) Click the Picture to Zoom In
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ARG44483 anti-INTU antibody IHC-P image
Immunohistochemistry: Human prostate cancer stained with ARG44483 anti-INTU antibody at 2 μg/mL dilution.
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ARG44483 anti-INTU antibody WB image
Western blot: SiHa and A431 stained with ARG44483 anti-INTU antibody at 0.5 μg/mL dilution.
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ARG44483 anti-INTU antibody FACS image
Flow Cytometry: MCF-7 stained with ARG44483 anti-INTU antibody at 1 μg/10^6 cells dilution.
