ARG66734
anti-INTS5 antibody
anti-INTS5 antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes INTS5 |
|---|---|
| 反应物种 | Hu, Ms |
| 应用 | IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | INTS5 |
| 抗原物种 | Human |
| 抗原 | Recombinant full length protein of Human INTS5. |
| 偶联标记 | Un-conjugated |
| 別名 | INT5; KIAA1698; Integrator complex subunit 5; Int5 |
应用说明
| 应用建议 |
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| 应用说明 | IHC-P: Antigen Retrieval: Heat mediation was performed in Sodium citrate buffer (pH 6.0). * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
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| 阳性对照 | MCF7, HT29 and Mouse liver | ||||||
| 实际分子量 | ~ 120 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | 0.42% Potassium phosphate (pH 7.3), 0.87% NaCl, 0.01% Sodium azide and 30% Glycerol. |
| 抗菌剂 | 0.01% Sodium azide |
| 稳定剂 | 30% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | INTS5 |
| 全名 | integrator complex subunit 5 |
| 背景介绍 | The Integrator complex is a complex that associates with the C-terminal domain of RNA polymerase II large subunit. This complex is brought to U1 and U2 small nuclear RNA genes, where it is involved in the transcription and processing of their transcripts. The protein encoded by this gene represents a subunit of the Integrator complex. [provided by RefSeq, Aug 2016] |
| 生物功能 | Component of the Integrator (INT) complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes (Probable). Mediates recruitment of cytoplasmic dynein to the nuclear envelope, probably as component of the INT complex (PubMed:23904267). [UniProt] |
| 细胞定位 | Nucleus membrane; Multi-pass membrane protein. Nucleus. Cytoplasm. [UniProt] |
| 预测分子量 | 108 kDa |
检测图片 (2) Click the Picture to Zoom In
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ARG66734 anti-INTS5 antibody IHC-P image
Immunohistochemistry: Formalin-fixed and paraffin-embedded Human esophageal cancer tissue section. Antigen Retrieval: Heat mediation was performed in Sodium citrate buffer (pH 6.0). The section was stained with ARG66734 anti-INTS5 antibody at room temperature. The section was counterstained with haematoxylin and mounted with DPX.
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ARG66734 anti-INTS5 antibody WB image
Western blot: MCF7, HT29 and Mouse liver whole cell lysates stained with ARG66734 anti-INTS5 antibody.
