ARG45757
anti-INTS4 antibody
anti-INTS4 antibody for Flow cytometry,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes INTS4 |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | FACS, IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | INTS4 |
| 抗原物种 | Human |
| 抗原 | Recombinant protein containing to human INTS4. |
| 偶联标记 | Un-conjugated |
| 別名 | INTS4; Integrator Complex Subunit 4; MST093; INT4; MGC16733; MSTP093; Int4 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| 实际分子量 | 140 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified |
| 缓冲液 | 0.2% Na2HPO4, 0.9% NaCl and 4% Trehalose. |
| 稳定剂 | 4% Trehalose |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | INTS4 |
| 全名 | Integrator Complex Subunit 4 |
| 背景介绍 | INTS4 is a subunit of the Integrator complex, which associates with the C-terminal domain of RNA polymerase II large subunit (POLR2A; MIM 180660) and mediates 3-prime end processing of small nuclear RNAs U1 (RNU1; MIM 180680) and U2 (RNU2; MIM 180690) (Baillat et al., 2005 [PubMed 16239144]).[supplied by OMIM, Mar 2008] |
| 生物功能 | Component of the Integrator (INT) complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes (Probable). Mediates recruitment of cytoplasmic dynein to the nuclear envelope, probably as component of the INT complex. [UniProt] |
| 细胞定位 | Nucleus. [UniProt] |
| 预测分子量 | 108 kDa |
| 翻译后修饰 | Acetylation; Isopeptide bond; Ubl conjugation. [UniProt] |
检测图片 (5) Click the Picture to Zoom In
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ARG45757 anti-INTS4 antibody IHC-P image
Immunohistochemistry: Human thyroid cancer stained with ARG45757 anti-INTS4 antibody at 2 μg/ml dilution.
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ARG45757 anti-INTS4 antibody WB image
Western blot: MCF-7 stained with ARG45757 anti-INTS4 antibody at 0.5 μg/ml dilution.
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ARG45757 anti-INTS4 antibody FACS image
Flow Cytometry: MCF-7 stained with ARG45757 anti-INTS4 antibody at 1 µg/10^6 cells dilution.
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ARG45757 anti-INTS4 antibody WB image
Western blot: Rat testis stained with ARG45757 anti-INTS4 antibody at 0.5 μg/ml dilution.
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ARG45757 anti-INTS4 antibody WB image
Western blot: Mouse testis stained with ARG45757 anti-INTS4 antibody at 0.5 μg/ml dilution.
