ARG40036
anti-INTS10 antibody
anti-INTS10 antibody for ICC/IF,Western blot and Human,Mouse
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes INTS10 |
|---|---|
| 反应物种 | Hu, Ms |
| 应用 | ICC/IF, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | INTS10 |
| 抗原物种 | Human |
| 抗原 | Recombinant fusion protein corresponding to aa. 451-710 of Human INTS10 (NP_060612.2). |
| 偶联标记 | Un-conjugated |
| 別名 | Int10; Integrator complex subunit 10; INT10; C8orf35 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| 阳性对照 | Mouse brain and HeLa | ||||||
| 实际分子量 | 70 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified. |
| 缓冲液 | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 50% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | INTS10 |
| 全名 | integrator complex subunit 10 |
| 背景介绍 | INTS10 is a subunit of the Integrator complex, which associates with the C-terminal domain of RNA polymerase II large subunit (POLR2A; MIM 180660) and mediates 3-prime end processing of small nuclear RNAs U1 (RNU1; MIM 180680) and U2 (RNU2; MIM 180690) (Baillat et al., 2005 [PubMed 16239144]).[supplied by OMIM, Mar 2008] |
| 生物功能 | Component of the Integrator complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes. [UniProt] |
| 细胞定位 | Nucleus. [UniProt] |
| 预测分子量 | 82 kDa |
检测图片 (2) Click the Picture to Zoom In
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ARG40036 anti-INTS10 antibody ICC/IF image
Immunofluorescence: A549 cells stained with ARG40036 anti-INTS10 antibody.
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ARG40036 anti-INTS10 antibody WB image
Western blot: 25 µg of Mouse brain and HeLa cell lysates stained with ARG40036 anti-INTS10 antibody at 1:1000 dilution.
