ARG40358
anti-INSRR / IRR (beta chain) antibody
anti-INSRR / IRR (beta chain) antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human
概述
产品描述 | Rabbit Polyclonal antibody recognizes INSRR / IRR (beta chain) |
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反应物种 | Hu |
应用 | IHC-P, WB |
宿主 | Rabbit |
克隆 | Polyclonal |
同位型 | IgG |
靶点名称 | INSRR / IRR (beta chain) |
抗原物种 | Human |
抗原 | KLH-conjugated synthetic peptide corresponding to aa. 668-702 of Human INSRR. |
偶联标记 | Un-conjugated |
別名 | Insulin receptor-related protein; IRR; EC 2.7.10.1; IR-related receptor; Insulin Receptor R |
应用说明
应用建议 |
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应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
阳性对照 | HeLa |
属性
形式 | Liquid |
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纯化 | Purification with Protein A and immunogen peptide. |
缓冲液 | PBS and 0.09% (W/V) Sodium azide. |
抗菌剂 | 0.09% (W/V) Sodium azide. |
存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
数据库连接 | |
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基因名称 | INSRR |
全名 | insulin receptor-related receptor |
生物功能 | Receptor with tyrosine-protein kinase activity. Functions as a pH sensing receptor which is activated by increased extracellular pH. Activates an intracellular signaling pathway that involves IRS1 and AKT1/PKB. [UniProt] |
细胞定位 | Membrane; Single-pass type I membrane protein. [UniProt] |
预测分子量 | 144 kDa |
翻译后修饰 | Autophosphorylated on tyrosine residues between pH 7.9 and pH 10.5. [UniProt] |
检测图片 (2) Click the Picture to Zoom In
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ARG40358 anti-INSRR / IRR (beta chain) antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Human breast carcinoma stained with ARG40358 anti-INSRR / IRR (beta chain) antibody at 1:25 dilution.
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ARG40358 anti-INSRR / IRR (beta chain) antibody WB image
Western blot: 20 µg of HeLa cell lysate stained with ARG40358 anti-INSRR / IRR (beta chain) antibody at 1:1000 dilution.