ARG42906
anti-INMT / TEMT antibody
anti-INMT / TEMT antibody for ICC/IF,Western blot and Human,Mouse
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes INMT / TEMT |
|---|---|
| 反应物种 | Hu, Ms |
| 应用 | ICC/IF, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | INMT / TEMT |
| 抗原物种 | Human |
| 抗原 | Recombinant fusion protein corresponding to aa. 1-263 of Human INMT / TEMT (NP_006765.4). |
| 偶联标记 | Un-conjugated |
| 別名 | Thioether S-methyltransferase; TEMT; Indolamine N-methyltransferase; EC 2.1.1.96; Indolethylamine N-methyltransferase; Aromatic alkylamine N-methyltransferase; Arylamine N-methyltransferase; Amine N-methyltransferase; EC 2.1.1.49 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| 阳性对照 | Mouse lung | ||||||
| 实际分子量 | ~ 30 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified. |
| 缓冲液 | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 50% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # O95050 Human Indolethylamine N-methyltransferase Swiss-port # P40936 Mouse Indolethylamine N-methyltransferase |
|---|---|
| 基因名称 | INMT |
| 全名 | indolethylamine N-methyltransferase |
| 背景介绍 | N-methylation of endogenous and xenobiotic compounds is a major method by which they are degraded. This gene encodes an enzyme that N-methylates indoles such as tryptamine. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the downstream MINDY4 (aka FAM188B) gene. In rodents and other mammals such as cetartiodactyla this gene is in the opposite orientation compared to its orientation in human and other primates and this gene appears to have been lost in carnivora and chiroptera. [provided by RefSeq, Jul 2019] |
| 生物功能 | Functions as thioether S-methyltransferase and is active with a variety of thioethers and the corresponding selenium and tellurium compounds, including 3-methylthiopropionaldehyde, dimethyl selenide, dimethyl telluride, 2-methylthioethylamine, 2-methylthioethanol, methyl-n-propyl sulfide and diethyl sulfide. Plays an important role in the detoxification of selenium compounds (By similarity). Catalyzes the N-methylation of tryptamine and structurally related compounds. [UniProt] |
| 细胞定位 | Cytoplasm. [UniProt] |
| 预测分子量 | 29 kDa |
检测图片 (2) Click the Picture to Zoom In
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ARG42906 anti-INMT / TEMT antibody ICC/IF image
Immunofluorescence: L929 cells stained with ARG42906 anti-INMT / TEMT antibody at 1:100 dilution.
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ARG42906 anti-INMT / TEMT antibody WB image
Western blot: 25 µg of Mouse lung lysate stained with ARG42906 anti-INMT / TEMT antibody at 1:3000 dilution.
