ARG45387

anti-IL31 antibody

anti-IL31 antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat

概述

产品描述 Rabbit Polyclonal antibody recognizes IL31
反应物种 Hu, Ms, Rat
应用 IHC-P, WB
宿主 Rabbit
克隆 Polyclonal
同位型 IgG
靶点名称 IL31
抗原物种 Human
抗原 Recombinant protein containing to human IL31.
偶联标记 Un-conjugated
別名 Interleukin-31; IL-31

应用说明

应用建议
应用 推荐稀释比
IHC-P0.5-1 μg/ml
WB0.1-0.5 μg/ml
应用说明 * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
实际分子量 29 kDa

属性

形式 Liquid
纯化 Affinity purified
缓冲液 0.9% NaCl, 0.2% Na2HPO4, 0.05% Sodium azide and 4% Trehalose.
抗菌剂 0.05% Sodium azide
稳定剂 4% Trehalose
浓度 0.5 mg/ml
存放说明 For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项 For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接

GeneID: 386653 Human IL31

GeneID: 76399 Mouse IL31

Swiss-port # Q6EAL8 Mouse Interleukin-31

Swiss-port # Q6EBC2 Human Interleukin-31

基因名称 IL31
全名 interleukin 31
背景介绍 IL31, which is made principally by activated Th2-type T cells, interacts with a heterodimeric receptor consisting of IL31RA (MIM 609510) and OSMR (MIM 601743) that is constitutively expressed on epithelial cells and keratinocytes. IL31 may be involved in the promotion of allergic skin disorders and in regulating other allergic diseases, such as asthma (Dillon et al., 2004 [PubMed 15184896]).[supplied by OMIM, Mar 2008]
生物功能 Activates STAT3 and possibly STAT1 and STAT5 through the IL31 heterodimeric receptor composed of IL31RA and OSMR. [UniProt]
细胞定位 Secreted. [UniProt]
预测分子量 18 kDa
翻译后修饰 Glycoprotein. [UniProt]

检测图片 (4) Click the Picture to Zoom In

  • ARG45387 anti-IL31 antibody IHC-P image

    Immunohistochemistry: Human colon cancer stained with ARG45387 anti-IL31 antibody at 1 μg/ml dilution.

  • ARG45387 anti-IL31 antibody IHC-P image

    Immunohistochemistry: Rat spleen stained with ARG45387 anti-IL31 antibody at 1 μg/ml dilution.

  • ARG45387 anti-IL31 antibody WB image

    Western blot: Rat spleen stained with ARG45387 anti-IL31 antibody at 0.5 μg/ml dilution.

  • ARG45387 anti-IL31 antibody IHC-P image

    Immunohistochemistry: Mouse spleen stained with ARG45387 anti-IL31 antibody at 1 μg/ml dilution.