ARG56791
anti-IL21 antibody (Biotin)
anti-IL21 antibody (Biotin) for ELISA,Western blot and Mouse
概述
| 产品描述 | Biotin-conjugated Rabbit Polyclonal antibody recognizes IL21 |
|---|---|
| 反应物种 | Ms |
| 应用 | ELISA, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | IL21 |
| 抗原物种 | Mouse |
| 抗原 | E.coli derived Recombinant Mouse IL-21. (MHKSSPQGPD RLLIRLRHLI DIVEQLKIYE NDLDPELLSA PQDVKGHCEH AAFACFQKAK LKPSNPGNNK TFIIDLVAQL RRRLPARRGG KKQKHIAKCP SCDSYEKRTP KEFLERLKWL LQKMIHQHLS) |
| 偶联标记 | Biotin |
| 別名 | Za11; IL-21; CVID11; Interleukin-21 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purified by affinity chromatography. |
| 缓冲液 | PBS (pH 7.2) |
| 浓度 | 1 mg/ml |
| 存放说明 | Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | Il21 |
| 全名 | interleukin 21 |
| 背景介绍 | This gene encodes a member of the common-gamma chain family of cytokines with immunoregulatory activity. The encoded protein plays a role in both the innate and adaptive immune responses by inducing the differentiation, proliferation and activity of multiple target cells including macrophages, natural killer cells, B cells and cytotoxic T cells. Dysregulation of this gene plays a role in multiple immune-mediated diseases including lupus, psoriasis and chronic inflammatory diseases. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011] |
| 生物功能 | Cytokine with immunoregulatory activity. May promote the transition between innate and adaptive immunity. Induces the production of IgG(1) and IgG(3) in B-cells (By similarity). May play a role in proliferation and maturation of natural killer (NK) cells in synergy with IL15. May regulate proliferation of mature B- and T-cells in response to activating stimuli. In synergy with IL15 and IL18 stimulates interferon gamma production in T-cells and NK cells. During T-cell mediated immune response may inhibit dendritic cells (DC) activation and maturation. [UniProt] |
| 预测分子量 | 19 kDa |
检测图片 (2) Click the Picture to Zoom In
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ARG56791 anti-IL21 antibody (Biotin) standard curve image
Direct ELISA: ARG56791 anti-IL21 antibody (Biotin) at 0.25 - 1.0 µg/ml results of a typical standard run with optical density.
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ARG56791 anti-IL21 antibody (Biotin) standard curve image
Sandwich ELISA: ARG56791 anti-IL21 antibody (Biotin) as a detection antibody at 0.25 - 1.0 µg/ml combined with ARG56681 anti-IL21 antibody as a capture antibody. Results of a typical standard run with optical density.
