ARG21487

anti-IL17 / IL17A antibody [TC11-8H4] (FITC)

anti-IL17 / IL17A antibody [TC11-8H4] (FITC) for ELISA,ELISPOT,Flow cytometry and Mouse

概述

产品描述 FITC-conjugated Rat Monoclonal antibody [TC11-8H4 ] recognizes IL17 / IL17A
反应物种 Ms
应用 ELISA, ELISPOT, FACS
特异性 Mouse IL-17A.
宿主 Rat
克隆 Monoclonal
克隆号 TC11-8H4
同位型 IgG1, kappa
靶点名称 IL17 / IL17A
抗原物种 Mouse
抗原 E. coli-expressed mouse IL-17
偶联标记 FITC
別名 IL-17A; Interleukin-17A; IL-17; CTLA8; IL17; CTLA-8; Cytotoxic T-lymphocyte-associated antigen 8

应用说明

应用建议
应用 推荐稀释比
ELISAAssay-dependent
ELISPOTAssay-dependent
FACS< 1 µg/10^6 cells
应用说明 * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

属性

形式 Liquid
缓冲液 PBS and 0.1% Sodium azide.
抗菌剂 0.1% Sodium azide
浓度 0.1 mg/ml
存放说明 Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项 For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接

GeneID: 16171 Mouse IL17A

Swiss-port # Q62386 Mouse Interleukin-17A

基因名称 IL17A
全名 interleukin 17A
背景介绍 The protein encoded by this gene is a proinflammatory cytokine produced by activated T cells. This cytokine regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis. [provided by RefSeq, Jul 2008]
生物功能 Induces stromal cells to produce proinflammatory and hematopoietic cytokines. Enhances the surface expression of ICAM1/intracellular adhesion molecule 1 in fibroblasts. [UniProt]
产品亮点 Related products:
IL17 antibodies; IL17 ELISA Kits; IL17 recombinant proteins; Anti-Rat IgG secondary antibodies;
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预测分子量 18 kDa
翻译后修饰 Found both in glycosylated and nonglycosylated forms.

检测图片 (1) Click the Picture to Zoom In

  • ARG21487 anti-IL17 / IL17A antibody [TC11-8H4] (FITC) FACS image

    Flow Cytometry: PMA and lonomycin-stimulated C57BL/6N Mouse T lymphocyte EL-4 cell line stained with ARG21487 anti-IL17 / IL17A antibody [TC11-8H4] (FITC).