ARG65674
anti-IL10 antibody [500-M128]
anti-IL10 antibody [500-M128] for Neutralizing,Sandwich ELISA,Western blot and Mouse,Rat
Cancer antibody; Immune System antibody
概述
| 产品描述 | Rat Monoclonal antibody [500-M128] recognizes IL10 |
|---|---|
| 反应物种 | Ms, Rat |
| 应用 | Neut, WB, sELISA |
| 宿主 | Rat |
| 克隆 | Monoclonal |
| 克隆号 | 500-M128 |
| 同位型 | IgG2a |
| 靶点名称 | IL10 |
| 抗原物种 | Mouse |
| 抗原 | E.coli derived recombinant mouse IL-10 |
| 偶联标记 | Un-conjugated |
| 別名 | IL10A; GVHDS; TGIF; IL-10; Cytokine synthesis inhibitory factor; CSIF; Interleukin-10 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purification with Protein G. |
| 缓冲液 | PBS (pH 7.2) |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | Il10 |
| 全名 | interleukin 10 |
| 背景介绍 | This gene encodes an anti-inflammatory cytokine that is a member of the class-2 cytokine family. The encoded protein is secreted by cells of both the innate and adaptive immune systems and is crucial for limiting the immune response to a broad range of pathogens. It also has been shown to suppress autoimmune responses. This protein mediates it's immunosuppressive signal through a specific interleukin 10 receptor complex. Aberrant functioning of this gene is associated with numerous immune disorders including graft-versus-host disease, and increased susceptibility to HIV-1 infection and rheumatoid arthritis. [provided by RefSeq, Sep 2015] |
| 生物功能 | Inhibits the synthesis of a number of cytokines, including IFN-gamma, IL-2, IL-3, TNF and GM-CSF produced by activated macrophages and by helper T-cells. [UniProt] |
| 研究领域 | Cancer antibody; Immune System antibody |
| 预测分子量 | 21 kDa |
检测图片 (2) Click the Picture to Zoom In
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ARG65674 anti-IL10 antibody [500-M128] WB image
Western blot: 250 - 0.24 ng (left to right) of recombinant Mouse IL-10 stained with ARG65674 anti-IL10 antibody [500-M128].
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ARG65674 anti-IL10 antibody [500-M128]standard curve image
ARG65674 anti-IL10 antibody [500-M128] results of a typical standard run with optical density reading at 405 - 650 nm.
