ARG67068
anti-IGF2BP3 antibody [SQab30341]
anti-IGF2BP3 antibody [SQab30341] for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Rat
概述
| 产品描述 | Recombinant Rabbit Monoclonal antibody [SQab30341] recognizes IGF2BP3 |
|---|---|
| 反应物种 | Hu, Rat |
| 应用 | IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Monoclonal |
| 克隆号 | SQab30341 |
| 同位型 | IgG |
| 靶点名称 | IGF2BP3 |
| 抗原物种 | Human |
| 抗原 | Recombinant protein fragment of IGF2BP3 |
| 偶联标记 | Un-conjugated |
| Protein Full name | IGF2BP3 |
| 別名 | IGF2BP3; Insulin Like Growth Factor 2 MRNA Binding Protein 3; IMP 3; IMP3; CT98; Insulin-Like Growth Factor 2 MRNA-Binding Protein 3; IGF-II MRNA-Binding Protein 3; IGF2 MRNA-Binding Protein 3; Cancer/Testis Antigen 98; VICKZ Family Member 3; VICKZ3; KOC1; KH Domain Containing Protein Overexpressed In Cancer; KH Domain-Containing Protein Overexpressed In Cancer; Insulin-Like Growth Factor 2 MRNA Binding Protein 3; IGF II MRNA Binding Protein 3; HKOC; KOC |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| 实际分子量 | 64 - 70 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purification with Protein A. |
| 缓冲液 | PBS, 0.01% Sodium azide, 40% Glycerol and 0.05% BSA. |
| 抗菌剂 | 0.01% Sodium azide |
| 稳定剂 | 40% Glycerol and 0.05% BSA |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # O00425 Human Insulin-like growth factor 2 mRNA-binding protein 3 |
|---|---|
| 基因名称 | IGF2BP3 |
| 全名 | Insulin Like Growth Factor 2 MRNA Binding Protein 3 |
| 背景介绍 | The protein encoded by this gene is primarily found in the nucleolus, where it can bind to the 5' UTR of the insulin-like growth factor II leader 3 mRNA and may repress translation of insulin-like growth factor II during late development. The encoded protein contains several KH domains, which are important in RNA binding and are known to be involved in RNA synthesis and metabolism. A pseudogene exists on chromosome 7, and there are putative pseudogenes on other chromosomes. [provided by RefSeq, Jul 2008] |
| 生物功能 | RNA-binding factor that may recruit target transcripts to cytoplasmic protein-RNA complexes (mRNPs). This transcript 'caging' into mRNPs allows mRNA transport and transient storage. It also modulates the rate and location at which target transcripts encounter the translational apparatus and shields them from endonuclease attacks or microRNA-mediated degradation. Preferentially binds to N6-methyladenosine (m6A)-containing mRNAs and increases their stability . [UniProt] |
| 细胞定位 | Cytoplasm, Nucleusd. [UniProt] |
| 预测分子量 | 64 kDa |
| 翻译后修饰 | Isopeptide bond; Phosphoprotein; Ubl conjugation. [UniProt] |
检测图片 (2) Click the Picture to Zoom In
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ARG67068 anti-IGF2BP3 antibody [SQab30341] IHC-P image
Immunohistochemistry: Human pancreatic cancer tissue stained with ARG67068 anti-IGF2BP3 antibody [SQab30341] at 1:100 dilution.
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ARG67068 anti-IGF2BP3 antibody [SQab30341] WB image (Customer review)
Western blot: HepG2 stained with ARG67068 anti-IGF2BP3 antibody [SQab30341] at 1:500 dilution.
客户反馈
Excellent
anti-IGF2BP3 antibody [SQab30341]
Application：WB
Sample：Rat Testis
Sample Loading Amount：10 μL
Primary Antibody Dilution Factor：1:500
Primary Antibody Incubation Time：overnight
Primary Antibody Incubation Temperature：4 ºC
Excellent
anti-IGF2BP3 antibody [SQab30341]
Application：WB
Sample：HeLa
Sample Loading Amount：10 μL
Primary Antibody Dilution Factor：1:500
Primary Antibody Incubation Time：overnight
Primary Antibody Incubation Temperature：4 ºC
