ARG65273
anti-IGF2BP1 / IMP1 antibody
anti-IGF2BP1 / IMP1 antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human
Gene Regulation antibody
概述
| 产品描述 | Goat Polyclonal antibody recognizes IGF2BP1 / IMP1. |
|---|---|
| 反应物种 | Hu |
| 预测物种 | Ms, Rat, Cow, Dog |
| 应用 | IHC-P, WB |
| 特异性 | This antibody is expected to recognize both reported isoforms (NP_006537.3; NP_001153895.1). |
| 宿主 | Goat |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | IGF2BP1 / IMP1 |
| 抗原物种 | Human |
| 抗原 | C-EKVFAEHKISYSGQ |
| 偶联标记 | Un-conjugated |
| 別名 | VICKZ1; CRDBP; IMP1; IMP-1; ZBP-1; ZBP1; CRD-BP; VICKZ family member 1; IGF2 mRNA-binding protein 1; IGF-II mRNA-binding protein 1; Zipcode-binding protein 1; Coding region determinant-binding protein; Insulin-like growth factor 2 mRNA-binding protein 1 |
应用说明
| 应用建议 |
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|---|---|---|---|---|---|---|---|
| 应用说明 | WB: Recommend incubate at RT for 1h. IHC-P: Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0). * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purified from goat serum by antigen affinity chromatography. |
| 缓冲液 | Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 0.5% BSA |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # Q9NZI8 Human Insulin-like growth factor 2 mRNA-binding protein 1 |
|---|---|
| 背景介绍 | This gene encodes a member of the insulin-like growth factor 2 mRNA-binding protein family. The protein encoded by this gene contains four K homology domains and two RNA recognition motifs. It functions by binding to the mRNAs of certain genes, including insulin-like growth factor 2, beta-actin and beta-transducin repeat-containing protein, and regulating their translation. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009] |
| 产品亮点 | Related news: m6A reader YTHDF2 in mRNA decay and aggresome formation; |
| 研究领域 | Gene Regulation antibody |
| 预测分子量 | 63 kDa |
| 翻译后修饰 | Phosphorylated. Phosphorylation may impair association with ACTB mRNA and hence abolishes translational repression (By similarity). |
检测图片 (2) Click the Picture to Zoom In
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ARG65273 anti-IGF2BP1 / IMP1 antibody WB image
Western Blot: K562 lysate (35 µg protein in RIPA buffer) stained with ARG65273 anti-IGF2BP1 / IMP1 antibody at 0.3 µg/ml dilution.
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ARG65273 anti-IGF2BP1 / IMP1 antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Human breast tissue. Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0). The tissue section was stained with ARG65273 anti-IGF2BP1 / IMP1 antibody at 3.75 µg/ml dilution followed by AP-staining.
