ARG56844
anti-IFITM1 antibody
anti-IFITM1 antibody for ICC/IF,Western blot and Human,Mouse
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes IFITM1 |
|---|---|
| 反应物种 | Hu, Ms |
| 预测物种 | Rat |
| 应用 | ICC/IF, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | IFITM1 |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide (16 aa) within aa. 40-90 of Human IFITM1. |
| 偶联标记 | Un-conjugated |
| 別名 | 9-27; DSPA2a; Leu-13 antigen; Dispanin subfamily A member 2a; Interferon-induced protein 17; Interferon-induced transmembrane protein 1; LEU13; CD antigen CD225; IFI17; CD225; Interferon-inducible protein 9-27 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| 阳性对照 | NIH-3T3 cell lysate |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | PBS and 0.02% Sodium azide. |
| 抗菌剂 | 0.02% Sodium azide |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # P13164 Human Interferon-induced transmembrane protein 1 Swiss-port # Q9D103 Mouse Interferon-induced transmembrane protein 1 |
|---|---|
| 基因名称 | IFITM1 |
| 全名 | interferon induced transmembrane protein 1 |
| 生物功能 | IFN-induced antiviral protein which inhibits the entry of viruses to the host cell cytoplasm, permitting endocytosis, but preventing subsequent viral fusion and release of viral contents into the cytosol. Active against multiple viruses, including influenza A virus, SARS coronavirus (SARS-CoV), Marburg virus (MARV), Ebola virus (EBOV), Dengue virus (DNV), West Nile virus (WNV), human immunodeficiency virus type 1 (HIV-1) and hepatitis C virus (HCV). Can inhibit: influenza virus hemagglutinin protein-mediated viral entry, MARV and EBOV GP1,2-mediated viral entry and SARS-CoV S protein-mediated viral entry. Also implicated in cell adhesion and control of cell growth and migration. Plays a key role in the antiproliferative action of IFN-gamma either by inhibiting the ERK activation or by arresting cell growth in G1 phase in a p53-dependent manner. Acts as a positive regulator of osteoblast differentiation. [UniProt] |
| 预测分子量 | 14 kDa |
| 翻译后修饰 | Palmitoylation on membrane-proximal cysteines controls clustering in membrane compartments and antiviral activity against influenza virus. |
检测图片 (3) Click the Picture to Zoom In
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ARG56844 anti-IFITM1 antibody ICC/IF image
Immunofluorescence: Jurkat cells stained with ARG56844 anti-IFITM1 antibody at 20 µg/ml dilution.
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ARG56844 anti-IFITM1 antibody WB image
Western blot: 3T3 cell lysate stained with ARG56844 anti-IFITM1 antibody at (A) 1 and (B) 2 µg/ml dilution.
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ARG56844 anti-IFITM1 antibody ICC/IF image
Immunocytochemistry: Jurkat cells stained with ARG56844 anti-IFITM1 antibody at 20 µg/ml dilution.
