概述

产品描述	Rabbit Polyclonal antibody recognizes IFIT2
反应物种	Hu
应用	WB
宿主	Rabbit
克隆	Polyclonal
同位型	IgG
靶点名称	IFIT2
抗原物种	Human
抗原	KLH-conjugated synthetic peptide corresponding to aa. 307-335 (Center) of Human IFIT2 (NP_001538.4).
偶联标记	Un-conjugated
別名	IFI-54K; IFIT-2; IFI-54; ISG54; ISG-54 K; cig42; Interferon-induced protein with tetratricopeptide repeats 2; Interferon-induced 54 kDa protein; P54; GARG-39; G10P2; IFI54; ISG-54K

应用说明

应用建议	应用 推荐稀释比 WB 1:1000
应用说明	* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
阳性对照	293

属性

纯化	Protein A purified
缓冲液	PBS and 0.09% (W/V) Sodium azide
抗菌剂	0.09% (W/V) Sodium azide
存放说明	For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项	For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接	GeneID: 3433 Human IFIT2 Swiss-port # P09913 Human Interferon-induced protein with tetratricopeptide repeats 2
基因名称	IFIT2
全名	interferon-induced protein with tetratricopeptide repeats 2
生物功能	IFN-induced antiviral protein which inhibits expression of viral messenger RNAs lacking 2'-O-methylation of the 5' cap. The ribose 2'-O-methylation would provide a molecular signature to distinguish between self and non-self mRNAs by the host during viral infection. Viruses evolved several ways to evade this restriction system such as encoding their own 2'-O-methylase for their mRNAs or by stealing host cap containing the 2'-O-methylation (cap snatching mechanism). Binds AU-rich viral RNAs, with or without 5' triphosphorylation, RNA-binding is required for antiviral activity. Can promote apoptosis. [UniProt]
细胞定位	Cytoplasm. Endoplasmic reticulum
研究领域	Immune System antibody; Signaling Transduction antibody
预测分子量	55 kDa

检测图片 (1) Click the Picture to Zoom In