ARG63890
anti-IDO1 / INDO antibody
anti-IDO1 / INDO antibody for Western blot and Human
Cell Biology and Cellular Response antibody; Metabolism antibody; Signaling Transduction antibody
概述
| 产品描述 | Goat Polyclonal antibody recognizes IDO1 / INDO |
|---|---|
| 反应物种 | Hu |
| 预测物种 | Ms, Rat, Dog |
| 应用 | WB |
| 宿主 | Goat |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | IDO1 / INDO |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide around the internal region of Human INDO / IDO. (NP_002155.1, CVLANWKKKDPNK) |
| 偶联标记 | Un-conjugated |
| 別名 | IDO-1; Indoleamine 2,3-dioxygenase 1; IDO; Indoleamine-pyrrole 2,3-dioxygenase; INDO; EC 1.13.11.52 |
应用说明
| 应用建议 |
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| 应用说明 | WB: Recommend incubate at RT for 1h. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
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| 实际分子量 | ~ 50 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purified from goat serum by antigen affinity chromatography. |
| 缓冲液 | Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 0.5% BSA |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 背景介绍 | This gene encodes indoleamine 2,3-dioxygenase (IDO) - a heme enzyme that catalyzes the first and rate-limiting step in tryptophan catabolism to N-formyl-kynurenine. This enzyme acts on multiple tryptophan substrates including D-tryptophan, L-tryptophan, 5-hydroxy-tryptophan, tryptamine, and serotonin. This enzyme is thought to play a role in a variety of pathophysiological processes such as antimicrobial and antitumor defense, neuropathology, immunoregulation, and antioxidant activity. Through its expression in dendritic cells, monocytes, and macrophages this enzyme modulates T-cell behavior by its peri-cellular catabolization of the essential amino acid tryptophan.[provided by RefSeq, Feb 2011] |
| 产品亮点 | Related products: INDO antibodies; Anti-Goat IgG secondary antibodies; Related news: More effective cocktail therapy for cancer immune evasion |
| 研究领域 | Cell Biology and Cellular Response antibody; Metabolism antibody; Signaling Transduction antibody |
| 预测分子量 | 45 kDa |
检测图片 (3) Click the Picture to Zoom In
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ARG63890 anti-IDO1 / INDO antibody IHC-P image
Immunohistochemistry: Human Placenta stained with ARG63890 anti-IDO1 / INDO antibody at 6 µg/ml dilution.
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ARG63890 anti-IDO1 / INDO antibody WB image
Western blot: Human lymph node stained with ARG63890 anti-IDO1 / INDO antibody at 0.5 µg/ml dilution.
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ARG63890 anti-IDO1 / INDO antibody WB image
Western blot: Human Placenta stained with ARG63890 anti-IDO1 / INDO antibody at 0.5 µg/ml dilution.
