ARG58092
anti-ID3 antibody
anti-ID3 antibody for ICC/IF,IHC-Formalin-fixed paraffin-embedded sections and Human,Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes ID3 |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | ICC/IF, IHC-P |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | ID3 |
| 抗原物种 | Human |
| 抗原 | Recombinant fusion protein corresponding to aa. 1-119 of Human ID3 (NP_002158.3). |
| 偶联标记 | Un-conjugated |
| 別名 | DNA-binding protein inhibitor ID-3; HEIR-1; Class B basic helix-loop-helix protein 25; ID-like protein inhibitor HLH 1R21; Inhibitor of DNA binding 3; Helix-loop-helix protein HEIR-1; bHLHb25; Inhibitor of differentiation 3 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified. |
| 缓冲液 | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 50% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | ID3 |
| 全名 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein |
| 背景介绍 | The protein encoded by this gene is a helix-loop-helix (HLH) protein that can form heterodimers with other HLH proteins. However, the encoded protein lacks a basic DNA-binding domain and therefore inhibits the DNA binding of any HLH protein with which it interacts. [provided by RefSeq, Aug 2011] |
| 生物功能 | Transcriptional regulator (lacking a basic DNA binding domain) which negatively regulates the basic helix-loop-helix (bHLH) transcription factors by forming heterodimers and inhibiting their DNA binding and transcriptional activity. Implicated in regulating a variety of cellular processes, including cellular growth, senescence, differentiation, apoptosis, angiogenesis, and neoplastic transformation. Involved in myogenesis by inhibiting skeletal muscle and cardiac myocyte differentiation and promoting muscle precursor cells proliferation. Inhibits the binding of E2A-containing protein complexes to muscle creatine kinase E-box enhancer. Regulates the circadian clock by repressing the transcriptional activator activity of the CLOCK-ARNTL/BMAL1 heterodimer. [UniProt] |
| 细胞定位 | Nucleus. [UniProt] |
| 预测分子量 | 13 kDa |
检测图片 (2) Click the Picture to Zoom In
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ARG58092 anti-ID3 antibody ICC/IF image
Immunofluorescence: HeLa cells stained with ARG58092 anti-ID3 antibody.
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ARG58092 anti-ID3 antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Mouse brain stained with ARG58092 anti-ID3 antibody at 1:200 dilution.
