ARG55588

anti-Hsp 40 antibody

anti-Hsp 40 antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse

Signaling Transduction antibody

概述

产品描述 Rabbit Polyclonal antibody recognizes Hsp 40
反应物种 Hu, Ms
应用 IHC-P, WB
宿主 Rabbit
克隆 Polyclonal
同位型 IgG
靶点名称 Hsp 40
抗原物种 Human
抗原 Recombinant protein encoding full length of Human HSP40.
偶联标记 Un-conjugated
別名 Hsp40; HSP40; DnaJ protein homolog 1; hDj-1; HSPF1; Human DnaJ protein 1; Hdj1; RSPH16B; Heat shock 40 kDa protein 1; DnaJ homolog subfamily B member 1; Heat shock protein 40; Sis1

应用说明

应用建议
应用 推荐稀释比
IHC-P1:50 - 1:100
WB1:1000
应用说明 * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
阳性对照 HeLa

属性

形式 Liquid
纯化 Purification with Protein G.
缓冲液 PBS and 0.09% (W/V) Sodium azide
抗菌剂 0.09% (W/V) Sodium azide
存放说明 For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项 For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接

GeneID: 3337 Human DNAJB1

GeneID: 81489 Mouse DNAJB1

Swiss-port # P25685 Human DnaJ homolog subfamily B member 1

Swiss-port # Q9QYJ3 Mouse DnaJ homolog subfamily B member 1

基因名称 DNAJB1
全名 DnaJ (Hsp40) homolog, subfamily B, member 1
背景介绍 This gene encodes a member of the DnaJ or Hsp40 (heat shock protein 40 kD) family of proteins. DNAJ family members are characterized by a highly conserved amino acid stretch called the 'J-domain' and function as one of the two major classes of molecular chaperones involved in a wide range of cellular events, such as protein folding and oligomeric protein complex assembly. The encoded protein is a molecular chaperone that stimulates the ATPase activity of Hsp70 heat-shock proteins in order to promote protein folding and prevent misfolded protein aggregation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015]
生物功能 Interacts with HSP70 and can stimulate its ATPase activity. Stimulates the association between HSC70 and HIP. [UniProt]
细胞定位 Cytoplasm. Nucleus. Nucleus, nucleolus. Note=Translocates rapidly from the cytoplasm to the nucleus, and especially to the nucleoli, upon heat shock
研究领域 Signaling Transduction antibody
预测分子量 38 kDa

检测图片 (2) Click the Picture to Zoom In

  • ARG55588 anti-Hsp 40 antibody IHC-P image

    Immunohistochemistry: Formalin-fixed and paraffin-embedded Human breast carcinoma tissue stained with ARG55588 anti-Hsp 40 antibody.

  • ARG55588 anti-Hsp 40 antibody WB image

    Western blot: 35 µg of HeLa cell lysate stained with ARG55588 anti-Hsp 40 antibody.