ARG67284
anti-Histone H3 dimethyl (Lys27) antibody [2H12]
anti-Histone H3 dimethyl (Lys27) antibody [2H12] for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
概述
| 产品描述 | Rabbit Monoclonal antibody [2H12] recognizes Histone H3 dimethyl (Lys27) |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Monoclonal |
| 克隆号 | 2H12 |
| 同位型 | IgG,Kappa |
| 靶点名称 | Histone H3 |
| 偶联标记 | Un-conjugated |
| 別名 | Histone H3/f; Histone H3.1; Histone H3/d; Histone H3/b; Histone H3/c; Histone H3/a; Histone H3/l; Histone H3/j; Histone H3/k; Histone H3/h; H3/A; H3FA; Histone H3/i |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purification with Protein A |
| 缓冲液 | PBS, 0.05% Proclin 300, 50% Glycerol and 0.05% BSA |
| 抗菌剂 | 0.05% Proclin 300 |
| 稳定剂 | 50% Glycerol and 0.05% BSA |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | HIST1H3A |
| 全名 | histone cluster 1, H3a |
| 背景介绍 | Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6p22-p21.3. [provided by RefSeq, Aug 2015] |
| 生物功能 | Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. [UniProt] |
| 预测分子量 | 15 kDa |
检测图片 (3) Click the Picture to Zoom In
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ARG67284 anti-Histone H3 dimethyl (Lys27) antibody [2H12] WB image
Western blot: Hela stained with ARG67284 anti-Histone H3 dimethyl (Lys27) antibody [2H12].
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ARG67284 anti-Histone H3 dimethyl (Lys27) antibody [2H12] WB image
Western blot: C6 stained with ARG67284 anti-Histone H3 dimethyl (Lys27) antibody [2H12].
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ARG67284 anti-Histone H3 dimethyl (Lys27) antibody [2H12] WB image
Western blot: NIH3T3 stained with ARG67284 anti-Histone H3 dimethyl (Lys27) antibody [2H12].
