ARG41930
anti-Histone H1.0 antibody
anti-Histone H1.0 antibody for ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes Histone H1.0 |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | ICC/IF, IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | Histone H1.0 |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide of Human Histone H1.0. |
| 偶联标记 | Un-conjugated |
| 別名 | Histone H1.0; H1FV; H10; 0; Histone H1; Histone H1' |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| 阳性对照 | Human kidney | ||||||||
| 实际分子量 | ~ 28 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified. |
| 缓冲液 | PBS (pH 7.4), 150 mM NaCl, 0.02% Sodium azide and 50% Glycerol. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 50% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | H1F0 |
| 全名 | H1 histone family, member 0 |
| 背景介绍 | Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H1 family. [provided by RefSeq, Jul 2008] |
| 生物功能 | Histones H1 are necessary for the condensation of nucleosome chains into higher-order structures. The H1F0 histones are found in cells that are in terminal stages of differentiation or that have low rates of cell division. [UniProt] |
| 细胞定位 | Nucleus. Chromosome. Note=The RNA edited version has been localized to nuclear speckles. During mitosis, it appears in the vicinity of condensed chromosomes. [UniProt] |
| 预测分子量 | 21 kDa |
| 翻译后修饰 | Phosphorylated on Ser-17 in RNA edited version. ADP-ribosylated on Ser-104 in response to DNA damage. [UniProt] |
检测图片 (3) Click the Picture to Zoom In
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ARG41930 anti-Histone H1.0 antibody ICC/IF image
Immunofluorescence: HepG2 cells stained with ARG41930 anti-Histone H1.0 antibody.
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ARG41930 anti-Histone H1.0 antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Human testis tissue stained with ARG41930 anti-Histone H1.0 antibody.
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ARG41930 anti-Histone H1.0 antibody WB image
Western blot: Human kidney lysate stained with ARG41930 anti-Histone H1.0 antibody.
