ARG67236
anti-Hexokinase 2 antibody
anti-Hexokinase 2 antibody for ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human
概述
| 产品描述 | Mouse Monoclonal antibody recognizes Hexokinase 2 |
|---|---|
| 反应物种 | Hu |
| 应用 | ICC/IF, IHC-P, WB |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 同位型 | IgG1 |
| 靶点名称 | Hexokinase 2 |
| 抗原物种 | Human |
| 偶联标记 | Un-conjugated |
| 別名 | HK2; Hexokinase 2; Muscle Form Hexokinase; Hexokinase Type II; Hexokinase-2; Hexokinase-B; EC 2.7.1.1; Hexokinase-2, Muscle; EC 2.7.1; HK II; HKII; HXK2 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified |
| 缓冲液 | PBS (pH 7.0), 0.025% ProClin 300 and 20% Glycerol. |
| 抗菌剂 | 0.025% ProClin 300 |
| 稳定剂 | 20% Glycerol |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | HK2 |
| 全名 | Hexokinase 2 |
| 背景介绍 | Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. This gene encodes hexokinase 2, the predominant form found in skeletal muscle. It localizes to the outer membrane of mitochondria. Expression of this gene is insulin-responsive, and studies in rat suggest that it is involved in the increased rate of glycolysis seen in rapidly growing cancer cells. [provided by RefSeq, Apr 2009] |
| 生物功能 | Plays a key role in maintaining the integrity of the outer mitochondrial membrane by preventing the release of apoptogenic molecules from the intermembrane space and subsequent apoptosis. [Uniprot] |
| 细胞定位 | Cytoplasm, Membrane, Mitochondrion, Mitochondrion outer membrane. [Uniprot] |
| 预测分子量 | 102 kDa |
| 翻译后修饰 | Acetylation. [Uniprot] |
检测图片 (3) Click the Picture to Zoom In
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ARG67236 anti-Hexokinase 2 antibody IHC-P image
Immunohistochemistry: Human epididymis stained with ARG67236 anti-Hexokinase 2 antibody.
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ARG67236 anti-Hexokinase 2 antibody ICC/IF image
Immunofluorescence: HeLa stained with ARG67236 anti-Hexokinase 2 antibody at 1:100 dilution.
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ARG67236 anti-Hexokinase 2 antibody WB image
Western blot: HeLa stained with ARG67236 anti-Hexokinase 2 antibody at 1:500 dilution.
