ARG57178
anti-Heme Oxygenase 1 antibody [1D6]
anti-Heme Oxygenase 1 antibody [1D6] for Flow cytometry,Western blot and Human
概述
| 产品描述 | Mouse Monoclonal antibody [1D6] recognizes Heme Oxygenase 1 |
|---|---|
| 反应物种 | Hu |
| 应用 | FACS, WB |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 克隆号 | 1D6 |
| 同位型 | IgG2a, kappa |
| 靶点名称 | Heme Oxygenase 1 |
| 抗原物种 | Human |
| 抗原 | Recombinant fragment around aa. 1-266 of Human Heme Oxygenase 1 |
| 偶联标记 | Un-conjugated |
| 別名 | bK286B10; Heme oxygenase 1; HO-1; EC 1.14.99.3; HMOX1D; HSP32 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purification with Protein A. |
| 缓冲液 | PBS (pH 7.4), 0.02% Sodium azide and 10% Glycerol. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 10% Glycerol |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | HMOX1 |
| 全名 | heme oxygenase 1 |
| 背景介绍 | Heme oxygenase, an essential enzyme in heme catabolism, cleaves heme to form biliverdin, which is subsequently converted to bilirubin by biliverdin reductase, and carbon monoxide, a putative neurotransmitter. Heme oxygenase activity is induced by its substrate heme and by various nonheme substances. Heme oxygenase occurs as 2 isozymes, an inducible heme oxygenase-1 and a constitutive heme oxygenase-2. HMOX1 and HMOX2 belong to the heme oxygenase family. [provided by RefSeq, Jul 2008] |
| 生物功能 | Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. Under physiological conditions, the activity of heme oxygenase is highest in the spleen, where senescent erythrocytes are sequestrated and destroyed. Exhibits cytoprotective effects since excess of free heme sensitizes cells to undergo apoptosis. [UniProt] |
| 产品亮点 | Related products: Heme Oxygenase 1 antibodies; Heme Oxygenase 1 ELISA Kits; Heme Oxygenase 1 Duos / Panels; Anti-Mouse IgG secondary antibodies; Related news: Keap1-Nrf2-ARE antibody panel is launched |
| 预测分子量 | 33 kDa |
检测图片 (2) Click the Picture to Zoom In
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ARG57178 anti-eme Oxygenase 1 antibody [1D6] FACS image
Flow Cytometry: HeLa cell line stained with ARG57178 anti-eme Oxygenase 1 antibody [1D6] at 2-5 µg for 1x10^6 cells (red line). Secondary antibody: Goat anti-Mouse IgG Alexa fluor 488 conjugate. Isotype control antibody: Mouse IgG (black line).
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ARG57178 anti-eme Oxygenase 1 antibody [1D6] WB image
Western blot: 40 µg of 1) HeLa, 2) A549, 3) 293T, 4) HepG2, and 5) TF-1 cell lysates stained with ARG57178 anti-eme Oxygenase 1 antibody [1D6] at 1:500.
