ARG45572
anti-Haspin antibody
anti-Haspin antibody for Flow cytometry,ICC/IF,Western blot and Human,Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes Haspin |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | FACS, ICC/IF, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | Haspin |
| 抗原物种 | Human |
| 抗原 | Recombinant protein containing to human Haspin. |
| 偶联标记 | Un-conjugated |
| 別名 | HASPIN; Histone H3 Associated Protein Kinase; GSG2; Haploid Germ Cell-Specific Nuclear Protein Kinase; Serine/Threonine-Protein Kinase Haspin; Germ Cell-Specific Gene 2 Protein; H-Haspin; Germ Cell Associated 2 (Haspin); Germ Cell Associated 2, Haspin; EC 2.7.11.1 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| 实际分子量 | 88 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified |
| 缓冲液 | 0.2% Na2HPO4, 0.9% NaCl and 4% Trehalose. |
| 稳定剂 | 4% Trehalose |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # Q8TF76 Human Serine/threonine-protein kinase haspin Swiss-port # Q9Z0R0 Mouse Serine/threonine-protein kinase haspin |
|---|---|
| 基因名称 | HASPIN |
| 全名 | Histone H3 Associated Protein Kinase |
| 背景介绍 | Enables ATP binding activity and histone H3T3 kinase activity. Involved in several processes, including mitotic sister chromatid cohesion; mitotic spindle assembly checkpoint signaling; and protein localization to chromosome, centromeric region. Located in centrosome; nucleoplasm; and spindle. [provided by Alliance of Genome Resources, Feb 2025] |
| 生物功能 | Serine/threonine-protein kinase that phosphorylates histone H3 at 'Thr-3' (H3T3ph) during mitosis. May act through H3T3ph to both position and modulate activation of AURKB and other components of the chromosomal passenger complex (CPC) at centromeres to ensure proper chromatid cohesion, metaphase alignment and normal progression through the cell cycle. ( HASP_HUMAN,Q8TF76 ). [UniProt] |
| 细胞定位 | Chromosome; Cytoplasm; Cytoskeleton; Nucleus. [UniProt] |
| 预测分子量 | 88 kDa |
| 翻译后修饰 | Phosphoprotein. [UniProt] |
检测图片 (5) Click the Picture to Zoom In
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ARG45572 anti-Haspin antibody ICC/IF image
Immunofluorescence: MG63 stained with ARG45572 anti-Haspin antibody at 5 μg/ml dilution.
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ARG45572 anti-Haspin antibody WB image
Western blot: K562 stained with ARG45572 anti-Haspin antibody at 0.5 μg/ml dilution.
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ARG45572 anti-Haspin antibody FACS image
Flow Cytometry: K562 stained with ARG45572 anti-Haspin antibody at 1 µg/10^6 cells dilution.
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ARG45572 anti-Haspin antibody WB image
Western blot: C6 stained with ARG45572 anti-Haspin antibody at 0.5 μg/ml dilution.
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ARG45572 anti-Haspin antibody WB image
Western blot: NIH/3T3 stained with ARG45572 anti-Haspin antibody at 0.5 μg/ml dilution.
