ARG59745

anti-HYAL1 antibody

anti-HYAL1 antibody for Western blot and Mouse,Rat

概述

产品描述 Rabbit Polyclonal antibody recognizes HYAL1
反应物种 Ms, Rat
应用 WB
宿主 Rabbit
克隆 Polyclonal
同位型 IgG
靶点名称 HYAL1
抗原物种 Mouse
抗原 Synthetic peptide corresponding to aa. 434-450 of Mouse HYAL1. (LKDRAQMAMKFRCRCYR)
偶联标记 Un-conjugated
別名 LUCA1; Lung carcinoma protein 1; EC 3.2.1.35; NAT6; Hyal-1; LuCa-1; HYAL-1; Hyaluronoglucosaminidase-1; Hyaluronidase-1; MPS9

应用说明

应用建议
应用 推荐稀释比
WB0.1 - 0.5 µg/ml
应用说明 * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

属性

形式 Liquid
纯化 Affinity purification with immunogen.
缓冲液 0.9% NaCl, 0.2% Na2HPO4, 0.05% Thimerosal, 0.05% Sodium azide and 5% BSA.
抗菌剂 0.05% Thimerosal and 0.05% Sodium azide
稳定剂 5% BSA
浓度 0.5 mg/ml
存放说明 For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项 For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接

GeneID: 15586 Mouse HYAL1

GeneID: 367166 Rat HYAL1

Swiss-port # Q76HN1 Rat Hyaluronidase-1

Swiss-port # Q91ZJ9 Mouse Hyaluronidase-1

基因名称 HYAL1
全名 hyaluronoglucosaminidase 1
背景介绍 This gene encodes a lysosomal hyaluronidase. Hyaluronidases intracellularly degrade hyaluronan, one of the major glycosaminoglycans of the extracellular matrix. Hyaluronan is thought to be involved in cell proliferation, migration and differentiation. This enzyme is active at an acidic pH and is the major hyaluronidase in plasma. Mutations in this gene are associated with mucopolysaccharidosis type IX, or hyaluronidase deficiency. The gene is one of several related genes in a region of chromosome 3p21.3 associated with tumor suppression. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
生物功能 May have a role in promoting tumor progression. May block the TGFB1-enhanced cell growth. [UniProt]
细胞定位 Secreted. Lysosome. [UniProt]
预测分子量 48 kDa

检测图片 (1) Click the Picture to Zoom In

  • ARG59745 anti-HYAL1 antibody WB image

    Western blot: NRK, Mouse liver, Mouse kidney and SP2/0 cell lysates stained with ARG59745 anti-HYAL1 antibody.