ARG59744
anti-HYAL1 antibody
anti-HYAL1 antibody for ICC/IF,IHC-Frozen sections,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes HYAL1 |
|---|---|
| 反应物种 | Hu |
| 应用 | ICC/IF, IHC-Fr, IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | HYAL1 |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide corresponding to aa. 32-47 of Human HYAL1. (FTTVWNANTQWCLERH) |
| 偶联标记 | Un-conjugated |
| 別名 | LUCA1; Lung carcinoma protein 1; EC 3.2.1.35; NAT6; Hyal-1; LuCa-1; HYAL-1; Hyaluronoglucosaminidase-1; Hyaluronidase-1; MPS9 |
应用说明
| 应用建议 |
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| 应用说明 | IHC-P: Antigen Retrieval: By heat mediation. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | 0.9% NaCl, 0.2% Na2HPO4, 0.05% Thimerosal, 0.05% Sodium azide and 5% BSA. |
| 抗菌剂 | 0.05% Thimerosal and 0.05% Sodium azide |
| 稳定剂 | 5% BSA |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | HYAL1 |
| 全名 | hyaluronoglucosaminidase 1 |
| 背景介绍 | This gene encodes a lysosomal hyaluronidase. Hyaluronidases intracellularly degrade hyaluronan, one of the major glycosaminoglycans of the extracellular matrix. Hyaluronan is thought to be involved in cell proliferation, migration and differentiation. This enzyme is active at an acidic pH and is the major hyaluronidase in plasma. Mutations in this gene are associated with mucopolysaccharidosis type IX, or hyaluronidase deficiency. The gene is one of several related genes in a region of chromosome 3p21.3 associated with tumor suppression. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
| 生物功能 | May have a role in promoting tumor progression. May block the TGFB1-enhanced cell growth. [UniProt] |
| 细胞定位 | Secreted. Lysosome. [UniProt] |
| 预测分子量 | 48 kDa |
检测图片 (4) Click the Picture to Zoom In
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ARG59744 anti-HYAL1 antibody ICC image
Immunocytochemistry: MCF7 cells stained with ARG59744 anti-HYAL1 antibody.
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ARG59744 anti-HYAL1 antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Human intestinal cancer tissue stained with ARG59744 anti-HYAL1 antibody.
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ARG59744 anti-HYAL1 antibody WB image
Western blot: HeLa, 22RV1 and MCF7 cell lysates stained with ARG59744 anti-HYAL1 antibody.
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ARG59744 anti-HYAL1 antibody IHC-Fr image
Immunohistochemistry: Frozen section of Human placenta stained with ARG59744 anti-HYAL1 antibody.
