ARG44504
anti-HSPA1L antibody
anti-HSPA1L antibody for Flow cytometry,ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes HSPA1L |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | FACS, ICC/IF, IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | HSPA1L |
| 抗原物种 | Human |
| 抗原 | Human HSPA1L recombinant protein |
| 偶联标记 | Un-conjugated |
| 別名 | HSPA1L; Heat Shock Protein Family A (Hsp70) Member 1 Like; HSP70-HOM; Hum70t; Heat Shock 70 KDa Protein 1-Like; Heat Shock 70kDa Protein 1-Like; eat Shock 70 KDa Protein 1-Hom; Heat Shock 70kD Protein-Like 1; Heat Shock 70 KDa Protein 1L; Epididymis Secretory Sperm Binding Protein; Heat Shock 10kDa Protein 1-Like; HSP70-Hom; HSP70-1L; HSP70 |
应用说明
| 应用建议 |
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| 应用说明 | The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified with Immunogen. |
| 缓冲液 | 0.9% NaCl, 0.2% Na2HPO4, 0.05% Sodium azide and 4% Trehalose. |
| 抗菌剂 | 0.05% Sodium azide |
| 稳定剂 | 4% Trehalose |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | HSPA1L |
| 全名 | Heat Shock Protein Family A (Hsp70) Member 1 Like |
| 背景介绍 | This gene encodes a 70kDa heat shock protein. In conjunction with other heat shock proteins, this protein stabilizes existing proteins against aggregation and mediates the folding of newly translated proteins in the cytosol and in organelles. The gene is located in the major histocompatibility complex class III region, in a cluster with two closely related genes which also encode isoforms of the 70kDa heat shock protein. |
| 生物功能 | Molecular chaperone implicated in a wide variety of cellular processes, including protection of the proteome from stress, folding and transport of newly synthesized polypeptides, activation of proteolysis of misfolded proteins and the formation and dissociation of protein complexes. Plays a pivotal role in the protein quality control system, ensuring the correct folding of proteins, the re-folding of misfolded proteins and controlling the targeting of proteins for subsequent degradation. This is achieved through cycles of ATP binding, ATP hydrolysis and ADP release, mediated by co-chaperones. The affinity for polypeptides is regulated by its nucleotide bound state. In the ATP-bound form, it has a low affinity for substrate proteins. However, upon hydrolysis of the ATP to ADP, it undergoes a conformational change that increases its affinity for substrate proteins. It goes through repeated cycles of ATP hydrolysis and nucleotide exchange, which permits cycles of substrate binding and release. |
| 预测分子量 | 70 kDa |
检测图片 (6) Click the Picture to Zoom In
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ARG44504 anti-HSPA1L antibody IHC-P image
Immunohistochemistry: Human ovarian cancer stained with ARG44504 anti-HSPA1L antibody at 2 μg/mL dilution.
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ARG44504 anti-HSPA1L antibody ICC/IF image
Immunofluorescence: HeLa stained with ARG44504 anti-HSPA1L antibody at 5 μg/mL dilution.
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ARG44504 anti-HSPA1L antibody WB image
Western blot: Hela and HepG2 stained with ARG44504 anti-HSPA1L antibody at 0.5 μg/mL dilution.
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ARG44504 anti-HSPA1L antibody FACS image
Flow Cytometry: HepG2 stained with ARG44504 anti-HSPA1L antibody at 1 μg/10^6 cells dilution.
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ARG44504 anti-HSPA1L antibody IHC-P image
Immunohistochemistry: Rat testis stained with ARG44504 anti-HSPA1L antibody at 2 μg/mL dilution.
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ARG44504 anti-HSPA1L antibody IHC-P image
Immunohistochemistry: Mouse testis stained with ARG44504 anti-HSPA1L antibody at 2 μg/mL dilution.
