ARG44488
anti-HSD3B7 antibody
anti-HSD3B7 antibody for ICC/IF,Western blot and Human
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes HSD3B7 |
|---|---|
| 反应物种 | Hu |
| 应用 | ICC/IF, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | HSD3B7 |
| 抗原物种 | Human |
| 抗原 | Human HSD3B7 recombinant protein |
| 偶联标记 | Un-conjugated |
| 別名 | HSD3B7; Hydroxy-Delta-5-Steroid Dehydrogenase, 3 Beta- And Steroid Delta-Isomerase 7; C(27)-3BETA-HSD; SDR11E3; Short Chain Dehydrogenase/Reductase Family 11E, Member 3; Cholest-5-Ene-3-Beta,7-Alpha-Diol 3-Beta-Dehydrogenase; 3-Beta-Hydroxy-Delta(5)-C27 Steroid Oxidoreductase; 3 Beta-Hydroxysteroid Dehydrogenase Type VII; 3 Beta-Hydroxysteroid Dehydrogenase Type 7; C(27) 3-Beta-HSD; 3-Beta-HSD VII; 3 Beta-Hydroxy-Delta 5-C27-Steroid Oxidoreductase |
应用说明
| 应用建议 |
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| 应用说明 | The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | 0.9% NaCl, 0.2% Na2HPO4, 0.05% Sodium azide and 4% Trehalose. |
| 抗菌剂 | 0.05% Sodium azide |
| 稳定剂 | 4% Trehalose |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
生物信息
| 数据库连接 |
Swiss-port # Q9H2F3 Human 3 beta-hydroxysteroid dehydrogenase type 7 |
|---|---|
| 基因名称 | HSD3B7 |
| 全名 | Hydroxy-Delta-5-Steroid Dehydrogenase, 3 Beta- And Steroid Delta-Isomerase 7 |
| 背景介绍 | This gene encodes an enzyme which is involved in the initial stages of the synthesis of bile acids from cholesterol and a member of the short-chain dehydrogenase/reductase superfamily. The encoded protein is a membrane-associated endoplasmic reticulum protein which is active against 7-alpha hydrosylated sterol substrates. Mutations in this gene are associated with a congenital bile acid synthesis defect which leads to neonatal cholestasis, a form of progressive liver disease. Multiple transcript variants encoding different isoforms have been found for this gene. |
| 生物功能 | The 3-beta-HSD enzymatic system plays a crucial role in the biosynthesis of all classes of hormonal steroids. HSD VII is active against four 7-alpha-hydroxylated sterols. Does not metabolize several different C(19/21) steroids as substrates. Involved in bile acid synthesis. |
| 细胞定位 | Endoplasmic reticulum, Membrane |
| 预测分子量 | 41 kDa |
检测图片 (2) Click the Picture to Zoom In
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ARG44488 anti-HSD3B7 antibody ICC/IF image
Immunofluorescence: A549 stained with ARG44488 anti-HSD3B7 antibody at 5 μg/mL dilution.
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ARG44488 anti-HSD3B7 antibody WB image
Western blot: HeLa, MCF-7 and HepG2 stained with ARG44488 anti-HSD3B7 antibody at 0.5 μg/mL dilution.
