ARG56108

anti-HPV16 L1 antibody [CamVir-1]

anti-HPV16 L1 antibody [CamVir-1] for ICC/IF,IHC-Formalin-fixed paraffin-embedded sections and HPV

概述

产品描述 Mouse Monoclonal antibody [CamVir-1] recognizes HPV16 L1
反应物种 HPV
应用 ICC/IF, IHC-P
宿主 Mouse
克隆 Monoclonal
克隆号 CamVir-1
同位型 IgG2a, kappa
靶点名称 HPV16 L1
抗原物种 Virus
抗原 Human papilloma virus type 16, major capsid protein L1.
偶联标记 Un-conjugated
別名 Major capsid protein L1

应用说明

交叉反应性说明 Virus (HPV-16)
应用建议
应用 推荐稀释比
ICC/IF0.5 - 1 µg/ml
IHC-P0.5 - 1 µg/ml
应用说明 IHC-P: Antigen Retrieval: Boil tissue section in 10 mM Citrate buffer (pH 6.0) for 10-20 min, followed by cooling at RT for 20 min.
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

属性

形式 Liquid
纯化 Purification with Protein G.
缓冲液 PBS (pH 7.4), 0.05% Sodium azide and 0.1 mg/ml BSA
抗菌剂 0.05% Sodium azide
稳定剂 0.1 mg/ml BSA
浓度 0.2 mg/ml
存放说明 For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项 For laboratory research only, not for drug, diagnostic or other use.

生物信息

基因名称 L1
全名 major capsid L1 protein
生物功能 Forms an icosahedral capsid with a T=7 symmetry and a 50 nm diameter. The capsid is composed of 72 pentamers linked to each other by disulfide bonds and associated with L2 proteins. Binds to heparan sulfate proteoglycans on cell surface of basal layer keratinocytes to provide initial virion attachment. This binding mediates a conformational change in the virus capsid that facilitates efficient infection. The virion enters the host cell via endocytosis. During virus trafficking, L1 protein dissociates from the viral DNA and the genomic DNA is released to the host nucleus. The virion assembly takes place within the cell nucleus. Encapsulates the genomic DNA together with protein L2. [UniProt]
细胞定位 Nuclear

检测图片 (1) Click the Picture to Zoom In

  • ARG56108 anti-HPV16 L1 antibody [CamVir-1] IHC-P image

    Immunohistochemistry: Formalin-fixed, paraffin-embedded Human cervix stained with ARG56108 anti-HPV16 L1 antibody [CamVir-1].