ARG45157

anti-HOOK3 antibody

anti-HOOK3 antibody for Flow cytometry,ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat

概述

产品描述 Rabbit Polyclonal antibody recognizes HOOK3
反应物种 Hu, Ms, Rat
应用 FACS, ICC/IF, IHC-P, WB
宿主 Rabbit
克隆 Polyclonal
同位型 IgG
靶点名称 HOOK3
抗原物种 Human
抗原 Recombinant protein containing to human HOOK3.
偶联标记 Un-conjugated
別名 HOOK3; hook microtubule tethering protein 3; Protein Hook homolog 3; h-hook3; Hhk3; HOOK3; HK3

应用说明

应用建议
应用 推荐稀释比
FACS1 - 3 µg/10^6 cells
ICC/IF2 μg/ml
IHC-P0.5-1 μg/ml
WB0.1-0.5 μg/ml
应用说明 * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
实际分子量 83 kDa

属性

形式 Liquid
纯化 Affinity purification with immunogen.
缓冲液 0.2% Na2HPO4, 0.9% NaCl, 0.05% Sodium azide and 4% Trehalose.
抗菌剂 0.05% Sodium azide
稳定剂 4% Trehalose
浓度 0.5 mg/ml
存放说明 For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项 For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接

GeneID: 320191 Mouse HOOK3

GeneID: 84376 Human HOOK3

Swiss-port # Q86VS8 Human Protein Hook homolog 3

Swiss-port # Q8BUK6 Mouse Protein Hook homolog 3

基因名称 HOOK3
全名 hook microtubule tethering protein 3
背景介绍 Hook proteins are cytosolic coiled-coil proteins that contain conserved N-terminal domains, which attach to microtubules, and more divergent C-terminal domains, which mediate binding to organelles. The Drosophila Hook protein is a component of the endocytic compartment.[supplied by OMIM, Apr 2004]
生物功能 Acts as an adapter protein linking the dynein motor complex to various cargos and converts dynein from a non-processive to a highly processive motor in the presence of dynactin. Facilitates the interaction between dynein and dynactin and activates dynein processivity (the ability to move along a microtubule for a long distance without falling off the track). Predominantly recruits 2 dyneins, which increases both the force and speed of the microtubule motor . [UniProt]
细胞定位 Cytoskeleton; Golgi apparatusCytoplasm; Microtubule. [UniProt]
预测分子量 83 kDa
翻译后修饰 Acetylation; Phosphoprotein. [UniProt]

检测图片 (8) Click the Picture to Zoom In

  • ARG45157 anti-HOOK3 antibody IHC-P image

    Immunohistochemistry: Human placenta stained with ARG45157 anti-HOOK3 antibody at 1 μg/ml dilution.

  • ARG45157 anti-HOOK3 antibody ICC/IF image

    Immunofluorescence: A431 stained with ARG45157 anti-HOOK3 antibody at 2 ug/ml dilution.

  • ARG45157 anti-HOOK3 antibody WB image

    Western blot: MOLT-4, RT4, and SiHa stained with ARG45157 anti-HOOK3 antibody at 0.5 μg/ml dilution.

  • ARG45157 anti-HOOK3 antibody FACS image

    Flow Cytometry: U87 stained with ARG45157 anti-HOOK3 antibody at 1 µg/10^6 cells dilution.

  • ARG45157 anti-HOOK3 antibody IHC-P image

    Immunohistochemistry: Mouse testis stained with ARG45157 anti-HOOK3 antibody at 1 μg/ml dilution.

  • ARG45157 anti-HOOK3 antibody WB image

    Western blot: Rat brain stained with ARG45157 anti-HOOK3 antibody at 0.5 μg/ml dilution.

  • ARG45157 anti-HOOK3 antibody IHC-P image

    Immunohistochemistry: Rat testis stained with ARG45157 anti-HOOK3 antibody at 1 μg/ml dilution.

  • ARG45157 anti-HOOK3 antibody WB image

    Western blot: Mouse brain stained with ARG45157 anti-HOOK3 antibody at 0.5 μg/ml dilution.