概述

产品描述	Mouse Monoclonal antibody recognizes HNMT
反应物种	Hu
应用	WB
宿主	Mouse
克隆	Monoclonal
克隆号	432CT31.4.2
同位型	IgG1
靶点名称	HNMT
抗原物种	Human
抗原	Purified His-tagged HNMT protein fragment.
偶联标记	Un-conjugated
別名	HMT; Histamine N-methyltransferase; EC 2.1.1.8; HNMT-S1; HNMT-S2

应用说明

应用建议	应用 推荐稀释比 WB 1:100 - 1:1000
应用说明	* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
阳性对照	HepG2

属性

形式	Liquid
纯化	This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
缓冲液	PBS and 0.09% (W/V) Sodium azide.
抗菌剂	0.09% (W/V) Sodium azide.
存放说明	For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项	For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接	GeneID: 3176 Human HNMT Swiss-port # P50135 Human Histamine N-methyltransferase
基因名称	HNMT
全名	histamine N-methyltransferase
背景介绍	In mammals, histamine is metabolized by two major pathways: N(tau)-methylation via histamine N-methyltransferase and oxidative deamination via diamine oxidase. This gene encodes the first enzyme which is found in the cytosol and uses S-adenosyl-L-methionine as the methyl donor. In the mammalian brain, the neurotransmitter activity of histamine is controlled by N(tau)-methylation as diamine oxidase is not found in the central nervous system. A common genetic polymorphism affects the activity levels of this gene product in red blood cells. Multiple alternatively spliced transcript variants that encode different proteins have been found for this gene. [provided by RefSeq, Jul 2008]
生物功能	Inactivates histamine by N-methylation. Plays an important role in degrading histamine and in regulating the airway response to histamine. [UniProt]
细胞定位	Cytoplasm.
预测分子量	33 kDa

检测图片 (1) Click the Picture to Zoom In