ARG45610
anti-HMGCS2 antibody
anti-HMGCS2 antibody for Flow cytometry,ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes HMGCS2 |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | FACS, ICC/IF, IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | HMGCS2 |
| 抗原物种 | Human |
| 抗原 | Recombinant protein containing to human HMGCS2. |
| 偶联标记 | Un-conjugated |
| 別名 | HMGCS2; 3-Hydroxy-3-Methylglutaryl-CoA Synthase 2; 3-Hydroxy-3-Methylglutaryl-Coenzyme A Synthase 2 (Mitochondrial); 3-Hydroxy-3-Methylglutaryl-CoA Synthase 2 (Mitochondrial); Hydroxymethylglutaryl-CoA Synthase, Mitochondrial; HMG-CoA Synthase; EC 2.3.3.10; 3-Hydroxy-3-Methylglutaryl Coenzyme A Synthase; Testicular Tissue Protein Li 88 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||||
| 实际分子量 | 50 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified |
| 缓冲液 | 0.2% Na2HPO4, 0.9% NaCl and 4% Trehalose. |
| 稳定剂 | 4% Trehalose |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # P54868 Human Hydroxymethylglutaryl-CoA synthase, mitochondrial Swiss-port # P54869 Mouse Hydroxymethylglutaryl-CoA synthase, mitochondrial |
|---|---|
| 基因名称 | HMGCS2 |
| 全名 | 3-Hydroxy-3-Methylglutaryl-CoA Synthase 2 |
| 背景介绍 | The protein encoded by this gene belongs to the HMG-CoA synthase family. It is a mitochondrial enzyme that catalyzes the first reaction of ketogenesis, a metabolic pathway that provides lipid-derived energy for various organs during times of carbohydrate deprivation, such as fasting. Mutations in this gene are associated with HMG-CoA synthase deficiency. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Oct 2009] |
| 生物功能 | Catalyzes the first irreversible step in ketogenesis, condensing acetyl-CoA to acetoacetyl-CoA to form HMG-CoA, which is converted by HMG-CoA reductase (HMGCR) into mevalonate. [UniProt] |
| 细胞定位 | Mitochondrion. [UniProt] |
| 预测分子量 | 57 kDa |
| 翻译后修饰 | Acetylation; Phosphoprotein. [UniProt] |
检测图片 (6) Click the Picture to Zoom In
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ARG45610 anti-HMGCS2 antibody IHC-P image
Immunohistochemistry: Human gastric cancer stained with ARG45610 anti-HMGCS2 antibody at 2 μg/ml dilution.
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ARG45610 anti-HMGCS2 antibody ICC/IF image
Immunofluorescence: CACO-2 stained with ARG45610 anti-HMGCS2 antibody at 5 μg/ml dilution.
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ARG45610 anti-HMGCS2 antibody WB image
Western blot: CACO-2 stained with ARG45610 anti-HMGCS2 antibody at 0.5 μg/ml dilution.
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ARG45610 anti-HMGCS2 antibody FACS image
Flow Cytometry: CACO-2 stained with ARG45610 anti-HMGCS2 antibody at 1 µg/10^6 cells dilution.
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ARG45610 anti-HMGCS2 antibody WB image
Western blot: Rat liver stained with ARG45610 anti-HMGCS2 antibody at 0.5 μg/ml dilution.
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ARG45610 anti-HMGCS2 antibody WB image
Western blot: Mouse liver stained with ARG45610 anti-HMGCS2 antibody at 0.5 μg/ml dilution.
