ARG56393
anti-HMGCL antibody
anti-HMGCL antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes HMGCL |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | HMGCL |
| 抗原物种 | Human |
| 抗原 | Recombinant protein of Human HMGCL |
| 偶联标记 | Un-conjugated |
| 別名 | EC 4.1.3.4; HMG-CoA lyase; 3-hydroxy-3-methylglutarate-CoA lyase; HL; Hydroxymethylglutaryl-CoA lyase, mitochondrial |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| 阳性对照 | SKOV3 |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 50% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | HMGCL |
| 全名 | 3-hydroxymethyl-3-methylglutaryl-CoA lyase |
| 背景介绍 | The protein encoded by this gene belongs to the HMG-CoA lyase family. It is a mitochondrial enzyme that catalyzes the final step of leucine degradation and plays a key role in ketone body formation. Mutations in this gene are associated with HMG-CoA lyase deficiency. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009] |
| 生物功能 | Key enzyme in ketogenesis (ketone body formation). Terminal step in leucine catabolism. Ketone bodies (beta-hydroxybutyrate, acetoacetate and acetone) are essential as an alternative source of energy to glucose, as lipid precursors and as regulators of metabolism. [UniProt] |
| 预测分子量 | 34 kDa |
检测图片 (2) Click the Picture to Zoom In
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ARG56393 anti-HMGCL antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Human kidney stained with ARG56393 anti-HMGCL antibody at 1:100 dilution.
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ARG56393 anti-HMGCL antibody WB image
Western blot: SKOV3 cell lysate stained with ARG56393 anti-HMGCL antibody.
