ARG45897
anti-HLCS antibody
anti-HLCS antibody for Western blot,IHC-Formalin-fixed paraffin-embedded sections,Flow cytometry and Human,Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes HLCS |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | FACS, IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | HLCS |
| 抗原物种 | Human |
| 抗原 | Recombinant protein containing to human HLCS. |
| 偶联标记 | Un-conjugated |
| 別名 | HLCS; Biotin--protein ligase; EC 6.3.4.-; Biotin apo-protein ligase [Includes: Biotin--[methylmalonyl-CoA-carboxytransferase] ligase; EC 6.3.4.9; Biotin--[propionyl-CoA-carboxylase [ATP-hydrolyzing]] ligase; EC 6.3.4.10; Holocarboxylase synthetase; HCS; Biotin--[methylcrotonoyl-CoA-carboxylase] ligase; EC 6.3.4.11; Biotin--[acetyl-CoA-carboxylase] ligase; EC 6.3.4.15] |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| 实际分子量 | 81 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity chromatography purified |
| 缓冲液 | 0.2% Na2HPO4, 0.9% NaCl and 4% Trehalose. |
| 稳定剂 | 4% Trehalose |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -22°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | HLCS |
| 全名 | Holocarboxylase Synthetase |
| 背景介绍 | This gene encodes an enzyme that catalyzes the binding of biotin to carboxylases and histones. The protein plays an important role in gluconeogenesis, fatty acid synthesis and branched chain amino acid catabolism. Defects in this gene are the cause of holocarboxylase synthetase deficiency. Multiple alternatively spliced variants, encoding the same protein, have been identified.[provided by RefSeq, Jun 2011] |
| 生物功能 | Biotin--protein ligase catalyzing the biotinylation of the 4 biotin-dependent carboxylases acetyl-CoA-carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, and methylcrotonyl-CoA carboxylase. [UniProt] |
| 细胞定位 | Cytoplasm; Mitochondrion. [UniProt] |
| 预测分子量 | 81 kDa |
| 翻译后修饰 | Phosphoprotein. [UniProt] |
检测图片 (5) Click the Picture to Zoom In
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ARG45897 anti-HLCS antibody WB image
Western blot: HEL stained with ARG45897 anti-HLCS antibody at 0.5 μg/ml dilution.
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ARG45897 anti-HLCS antibody FACS image
Flow Cytometry: RT4 stained with ARG45897 anti-HLCS antibody at 1 µg/10^6 cells dilution.
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ARG45897 anti-HLCS antibody IHC-P image
Immunohistochemistry: Rat ovary stained with ARG45897 anti-HLCS antibody at 2 μg/ml dilution.
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ARG45897 anti-HLCS antibody WB image
Western blot: Rat heart stained with ARG45897 anti-HLCS antibody at 0.5 μg/ml dilution.
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ARG45897 anti-HLCS antibody WB image
Western blot: Mouse heart stained with ARG45897 anti-HLCS antibody at 0.5 μg/ml dilution.
