概述

产品描述	Mouse Monoclonal antibody recognizes HLA G
反应物种	Hu
应用	WB
宿主	Mouse
克隆	Monoclonal
克隆号	800CT6.4.2
同位型	IgG1
靶点名称	HLA G
抗原物种	Human
抗原	Purified His-tagged Human HLA-G.
偶联标记	Un-conjugated
別名	HLA G antigen; MHC class I antigen G; HLA class I histocompatibility antigen, alpha chain G; MHC-G

应用说明

应用建议	应用 推荐稀释比 WB 1:1000
应用说明	* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
阳性对照	A549

属性

形式	Liquid
纯化	Purification with Protein G.
缓冲液	PBS and 0.09% (W/V) Sodium azide.
抗菌剂	0.09% (W/V) Sodium azide.
存放说明	For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项	For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接	GeneID: 3135 Human HLA-G Swiss-port # P17693 Human HLA class I histocompatibility antigen, alpha chain G
基因名称	HLA-G
全名	major histocompatibility complex, class I, G
背景介绍	HLA-G belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. HLA-G is expressed on fetal derived placental cells. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domain, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exon 6 encodes the cytoplasmic tail. [provided by RefSeq, Jul 2008]
生物功能	Involved in the presentation of foreign antigens to the immune system. Plays a role in maternal tolerance of the fetus by mediating protection from the deleterious effects of natural killer cells, cytotoxic T-lymphocytes, macrophages and mononuclear cells. [UniProt]
细胞定位	Membrane; Single-pass type I membrane protein
预测分子量	38 kDa

检测图片 (1) Click the Picture to Zoom In