ARG41040

anti-HIRIP3 antibody

anti-HIRIP3 antibody for ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat

概述

产品描述 Rabbit Polyclonal antibody recognizes HIRIP3
反应物种 Hu, Ms, Rat
应用 ICC/IF, IHC-P, WB
宿主 Rabbit
克隆 Polyclonal
同位型 IgG
靶点名称 HIRIP3
抗原物种 Human
抗原 Recombinant fusion protein corresponding to aa. 417-556 of Human HIRIP3 (NP_003600.2).
偶联标记 Un-conjugated
別名 HIRA-interacting protein 3

应用说明

应用建议
应用 推荐稀释比
ICC/IF1:50 - 1:200
IHC-P1:50 - 1:200
WB1:500 - 1:2000
应用说明 * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
阳性对照 Mouse skeletal muscle
实际分子量 62 kDa

属性

形式 Liquid
纯化 Affinity purified.
缓冲液 PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol.
抗菌剂 0.02% Sodium azide
稳定剂 50% Glycerol
存放说明 For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项 For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接

GeneID: 233876 Mouse HIRIP3

GeneID: 8479 Human HIRIP3

Swiss-port # Q8BLH7 Mouse HIRA-interacting protein 3

Swiss-port # Q9BW71 Human HIRA-interacting protein 3

基因名称 HIRIP3
全名 HIRA interacting protein 3
背景介绍 The HIRA protein shares sequence similarity with Hir1p and Hir2p, the two corepressors of histone gene transcription characterized in the yeast, Saccharomyces cerevisiae. The structural features of the HIRA protein suggest that it may function as part of a multiprotein complex. Several cDNAs encoding HIRA-interacting proteins, or HIRIPs, have been identified. In vitro, the protein encoded by this gene binds HIRA, as well as H2B and H3 core histones, indicating that a complex containing HIRA-HIRIP3 could function in some aspects of chromatin and histone metabolism. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.[provided by RefSeq, Aug 2011]
生物功能 May play a role in chromatin function and histone metabolism via its interaction with HIRA and histones. [UniProt]
细胞定位 Nucleus. Note=Nuclear throughout the cell cycle and is excluded from condensed chromatin during mitosis. [UniProt]
预测分子量 62 kDa
翻译后修饰 Phosphorylated by CK2. [UniProt]

检测图片 (3) Click the Picture to Zoom In

  • ARG41040 anti-HIRIP3 antibody ICC/IF image

    Immunofluorescence: U2OS cells stained with ARG41040 anti-HIRIP3 antibody.

  • ARG41040 anti-HIRIP3 antibody IHC-P image

    Immunohistochemistry: Paraffin-embedded Human kidney stained with ARG41040 anti-HIRIP3 antibody at 1:100 dilution.

  • ARG41040 anti-HIRIP3 antibody WB image

    Western blot: 25 µg of Mouse skeletal muscle lysate stained with ARG41040 anti-HIRIP3 antibody at 1:1000 dilution.