ARG64902
anti-HIPPI antibody
anti-HIPPI antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse
Neuroscience antibody
概述
| 产品描述 | Goat Polyclonal antibody recognizes HIPPI |
|---|---|
| 反应物种 | Hu, Ms |
| 预测物种 | Cow, Rat |
| 应用 | IHC-P, WB |
| 宿主 | Goat |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | HIPPI |
| 抗原物种 | Human |
| 抗原 | C-EQPQEYDDPNATISN |
| 偶联标记 | Un-conjugated |
| 別名 | HIPPI; ESRRBL1; Dermal papilla-derived protein 8; Intraflagellar transport protein 57 homolog; HIP1-interacting protein; MHS4R2; Estrogen-related receptor beta-like protein 1 |
应用说明
| 应用建议 |
|
||||||
|---|---|---|---|---|---|---|---|
| 应用说明 | WB: Recommend incubate at RT for 1h. IHC-P: Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0). * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purified from goat serum by antigen affinity chromatography. |
| 缓冲液 | Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 0.5% BSA |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # Q8BXG3 Mouse Intraflagellar transport protein 57 homolog Swiss-port # Q9NWB7 Human Intraflagellar transport protein 57 homolog |
|---|---|
| 基因名称 | IFT57 |
| 全名 | intraflagellar transport 57 |
| 生物功能 | Required for the formation of cilia. Plays an indirect role in sonic hedgehog signaling, cilia being required for all activity of the hedgehog pathway (By similarity). Has pro-apoptotic function via its interaction with HIP1, leading to recruit caspase-8 (CASP8) and trigger apoptosis. Has the ability to bind DNA sequence motif 5'-AAAGACATG-3' present in the promoter of caspase genes such as CASP1, CASP8 and CASP10, suggesting that it may act as a transcription regulator; however the relevance of such function remains unclear. [UniProt] |
| 研究领域 | Neuroscience antibody |
| 预测分子量 | 49 kDa |
检测图片 (2) Click the Picture to Zoom In
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ARG64902 anti-HIPPI antibody WB image
Western Blot: Mouse Brain lysate (35 µg protein in RIPA buffer) stained with ARG64902 anti-HIPPI antibody at 1 µg/ml dilution.
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ARG64902 anti-HIPPI antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Human testes tissue. Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0). The tissue section was stained with ARG64902 anti-HIPPI antibody at 5 µg/ml dilution followed by AP-staining.
