ARG58963
anti-HELLS / SMARCA6 antibody
anti-HELLS / SMARCA6 antibody for Immunoprecipitation,Western blot and Human,Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes HELLS / SMARCA6 |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | IP, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | HELLS / SMARCA6 |
| 抗原物种 | Human |
| 抗原 | Recombinant fusion protein corresponding to aa. 719-838 of Human HELLS / SMARCA6 (NP_060533.2). |
| 偶联标记 | Un-conjugated |
| 別名 | SWI/SNF2-related matrix-associated actin-dependent regulator of chromatin subfamily A member 6; PASG; Nbla10143; EC 3.6.4.-; LSH; Lymphoid-specific helicase; Proliferation-associated SNF2-like protein; SMARCA6 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| 阳性对照 | MCF7 | ||||||
| 实际分子量 | 120 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified. |
| 缓冲液 | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 50% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | HELLS |
| 全名 | helicase, lymphoid-specific |
| 背景介绍 | This gene encodes a lymphoid-specific helicase. Other helicases function in processes involving DNA strand separation, including replication, repair, recombination, and transcription. This protein is thought to be involved with cellular proliferation and may play a role in leukemogenesis. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jan 2014] |
| 生物功能 | Plays an essential role in normal development and survival. Involved in regulation of the expansion or survival of lymphoid cells. Required for de novo or maintenance DNA methylation. May control silencing of the imprinted CDKN1C gene through DNA methylation. May play a role in formation and organization of heterochromatin, implying a functional role in the regulation of transcription and mitosis (By similarity). [UniProt] |
| 细胞定位 | Nucleus. [UniProt] |
| 预测分子量 | 97 kDa |
检测图片 (2) Click the Picture to Zoom In
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ARG58963 anti-HELLS / SMARCA6 antibody WB image
Western blot: 25 µg of MCF7 cell lysate stained with ARG58963 anti-HELLS / SMARCA6 antibody at 1:1000 dilution.
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ARG58963 anti-HELLS / SMARCA6 antibody IP image
Immunoprecipitation: 200 µg extracts of 293T cells were immunoprecipitated and stained with ARG58963 anti-HELLS / SMARCA6 antibody at 1:1000 dilution.
