ARG41770
anti-HDAC11 antibody
anti-HDAC11 antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes HDAC11 |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | HDAC11 |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide corresponding to aa. 47-81 of Human HDAC11. (NFLKEEKLLSDSMLVEAREASEEDLLVVHTRRYLN) |
| 偶联标记 | Un-conjugated |
| 別名 | HD11; EC 3.5.1.98; Histone deacetylase 11 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| 实际分子量 | ~ 39 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | 0.2% Na2HPO4, 0.9% NaCl, 0.05% Sodium azide and 5% BSA. |
| 抗菌剂 | 0.05% Sodium azide |
| 稳定剂 | 5% BSA |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | HDAC11 |
| 全名 | histone deacetylase 11 |
| 背景介绍 | This gene encodes a class IV histone deacetylase. The encoded protein is localized to the nucleus and may be involved in regulating the expression of interleukin 10. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Apr 2009] |
| 生物功能 | Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. [UniProt] |
| 细胞定位 | Nucleus. Note=Predominantly nuclear. [UniProt] |
| 预测分子量 | 39 kDa |
检测图片 (4) Click the Picture to Zoom In
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ARG41770 anti-HDAC11 antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Mouse brain tissue stained with ARG41770 anti-HDAC11 antibody.
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ARG41770 anti-HDAC11 antibody WB image
Western blot: 50 µg of Rat skeletal muscle, 50 µg of Rat kidney, 50 µg of Rat cardiac muscle, 40 µg of NRK, 40 µg of 293T, 40 µg of HeLa and 40 µg of MCF7 whole cell lysates stained with ARG41770 anti-HDAC11 antibody at 0.5 µg/ml dilution.
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ARG41770 anti-HDAC11 antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Rat brain tissue stained with ARG41770 anti-HDAC11 antibody.
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ARG41770 anti-HDAC11 antibody WB image
Western blot: 50 µg of samples under reducing conditions. Rat brain and Mouse brain lysates stained with ARG41770 anti-HDAC11 antibody at 0.5 µg/ml dilution, overnight at 4°C.
