ARG41799
anti-HDAC10 antibody
anti-HDAC10 antibody for ICC/IF,Immunoprecipitation,Western blot and Human,Mouse
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes HDAC10 |
|---|---|
| 反应物种 | Hu, Ms |
| 应用 | ICC/IF, IP, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | HDAC10 |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide of Human HDAC10. |
| 偶联标记 | Un-conjugated |
| 別名 | HD10; EC 3.5.1.98; Histone deacetylase 10 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| 阳性对照 | HeLa | ||||||||
| 实际分子量 | ~ 75 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified. |
| 缓冲液 | PBS (pH 7.4), 150 mM NaCl, 0.02% Sodium azide and 50% Glycerol. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 50% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | HDAC10 |
| 全名 | histone deacetylase 10 |
| 背景介绍 | The protein encoded by this gene belongs to the histone deacetylase family, members of which deacetylate lysine residues on the N-terminal part of the core histones. Histone deacetylation modulates chromatin structure, and plays an important role in transcriptional regulation, cell cycle progression, and developmental events. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011] |
| 生物功能 | Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. [UniProt] |
| 细胞定位 | Cytoplasm. Nucleus. Note=Excluded from the nucleoli. [UniProt] |
| 预测分子量 | 71 kDa |
检测图片 (2) Click the Picture to Zoom In
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ARG41799 anti-HDAC10 antibody ICC/IF image
Immunofluorescence: HeLa cells stained with ARG41799 anti-HDAC10 antibody (green). Nuclear staining (blue).
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ARG41799 anti-HDAC10 antibody WB image
Western blot: HeLa cell lysate stained with ARG41799 anti-HDAC10 antibody.
