ARG57756

anti-HCLS1 antibody

anti-HCLS1 antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse

概述

产品描述 Rabbit Polyclonal antibody recognizes HCLS1
反应物种 Hu, Ms
应用 IHC-P, WB
宿主 Rabbit
克隆 Polyclonal
同位型 IgG
靶点名称 HCLS1
抗原物种 Human
抗原 Recombinant fusion protein corresponding to aa. 1-280 of Human HCLS1 (NP_005326.2).
偶联标记 Un-conjugated
別名 p75; LckBP1; Hematopoietic cell-specific LYN substrate 1; HS1; Hematopoietic lineage cell-specific protein; CTTNL; lckBP1

应用说明

应用建议
应用 推荐稀释比
IHC-P1:50 - 1:200
WB1:500 - 1:2000
应用说明 * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
阳性对照 Jurkat

属性

形式 Liquid
纯化 Affinity purified.
缓冲液 PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol.
抗菌剂 0.02% Sodium azide
稳定剂 50% Glycerol
存放说明 For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项 For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接

GeneID: 15163 Mouse HCLS1

GeneID: 3059 Human HCLS1

Swiss-port # P14317 Human Hematopoietic lineage cell-specific protein

Swiss-port # P49710 Mouse Hematopoietic lineage cell-specific protein

基因名称 HCLS1
全名 hematopoietic cell-specific Lyn substrate 1
生物功能 Substrate of the antigen receptor-coupled tyrosine kinase. Plays a role in antigen receptor signaling for both clonal expansion and deletion in lymphoid cells. May also be involved in the regulation of gene expression. [UniProt]
细胞定位 Cytoplasm, Membrane, Mitochondrion, Peripheral membrane protein. [UniProt]
预测分子量 54 kDa
翻译后修饰 Phosphorylated by FES (By similarity). Phosphorylated by LYN, FYN and FGR after cross-linking of surface IgM on B-cells. Phosphorylation by LYN, FYN and FGR requires prior phosphorylation by SYK or FES. [UniProt]

检测图片 (2) Click the Picture to Zoom In

  • ARG57756 anti-HCLS1 antibody IHC-P image

    Immunohistochemistry: Paraffin-embedded Mouse kidney stained with ARG57756 anti-HCLS1 antibody at 1:100 dilution.

  • ARG57756 anti-HCLS1 antibody WB image

    Western blot: 25 µg of Jurkat cell lysate stained with ARG57756 anti-HCLS1 antibody at 1:1000 dilution.