ARG44201
anti-HB EGF antibody
anti-HB EGF antibody for Western blot and Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes HB EGF |
|---|---|
| 反应物种 | Ms, Rat |
| 应用 | WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | HB EGF |
| 抗原物种 | Mouse |
| 抗原 | Recombinant protein of Mouse HB EGF |
| 偶联标记 | Un-conjugated |
| Protein Full name | Proheparin-binding EGF-like growth factor |
| 別名 | HBEGF; Heparin Binding EGF Like Growth Factor; HEGFL; DTR; DTS; Diphtheria Toxin Receptor (Heparin-Binding Epidermal Growth Factor-Like Growth Factor); Diphtheria Toxin Receptor (Heparin-Binding EGF-Like Growth Factor); Proheparin-Binding EGF-Like Growth Factor; Heparin-Binding Epidermal Growth Factor; Heparin-Binding EGF-Like Growth Factor; DTSF |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | 0.9% NaCl, 0.2% Na2HPO4, 0.05% Sodium azide and 5% BSA. |
| 抗菌剂 | 0.05% Sodium azide |
| 稳定剂 | 5% BSA |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 基因名称 | HBEGF |
|---|---|
| 全名 | Heparin-Binding Egf-Like Growth Factor |
| 背景介绍 | Enables growth factor activity and heparin binding activity. Involved in several processes, including epidermal growth factor receptor signaling pathway; positive regulation of protein kinase B signaling; and positive regulation of wound healing. Located in cell surface and extracellular space. Implicated in glomerulosclerosis and perinatal necrotizing enterocolitis. |
| 生物功能 | Growth factor that mediates its effects via EGFR, ERBB2 and ERBB4. Required for normal cardiac valve formation and normal heart function. Promotes smooth muscle cell proliferation. May be involved in macrophage-mediated cellular proliferation. It is mitogenic for fibroblasts, but not endothelial cells. It is able to bind EGF receptor/EGFR with higher affinity than EGF itself and is a far more potent mitogen for smooth muscle cells than EGF. Also acts as a diphtheria toxin receptor. |
| 细胞定位 | Cell membrane, Membrane, Secreted |
| 预测分子量 | 23 kDa |
| 翻译后修饰 | Disulfide bond, Glycoprotein |
检测图片 (2) Click the Picture to Zoom In
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ARG44201 anti-HB EGF antibody WB image
Western blot: Rat heart stained with ARG44201 anti-HB EGF antibody at 0.5 μg/mL dilution.
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ARG44201 anti-HB EGF antibody WB image
Western blot: Mouse heart stained with ARG44201 anti-HB EGF antibody at 0.5 μg/mL dilution.
