概述

产品描述	Rabbit Polyclonal antibody recognizes HAS3
反应物种	Hu, Ms, Rat
应用	ICC/IF, WB
宿主	Rabbit
克隆	Polyclonal
同位型	IgG
靶点名称	HAS3
抗原物种	Human
抗原	Recombinant fusion protein corresponding to aa. 67-281 of Human HAS3 (NP_619515.1).
偶联标记	Un-conjugated
別名	HA synthase 3; EC 2.4.1.212; Hyaluronic acid synthase 3; Hyaluronate synthase 3; Hyaluronan synthase 3

应用说明

应用建议	应用 推荐稀释比 ICC/IF 1:50 - 1:200 WB 1:500 - 1:2000
应用说明	* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
阳性对照	Rat heart, Mouse heart and SW480

属性

形式	Liquid
纯化	Affinity purified.
缓冲液	PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol.
抗菌剂	0.02% Sodium azide
稳定剂	50% Glycerol
存放说明	For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项	For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接	GeneID: 15118 Mouse HAS3 GeneID: 3038 Human HAS3 Swiss-port # O00219 Human Hyaluronan synthase 3 Swiss-port # O08650 Mouse Hyaluronan synthase 3
基因名称	HAS3
全名	hyaluronan synthase 3
背景介绍	The protein encoded by this gene is involved in the synthesis of the unbranched glycosaminoglycan hyaluronan, or hyaluronic acid, which is a major constituent of the extracellular matrix. This gene is a member of the NODC/HAS gene family. Compared to the proteins encoded by other members of this gene family, this protein appears to be more of a regulator of hyaluronan synthesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2010]
生物功能	Catalyzes the addition of GlcNAc or GlcUA monosaccharides to the nascent hyaluronan polymer. Therefore, it is essential to hyaluronan synthesis a major component of most extracellular matrices that has a structural role in tissues architectures and regulates cell adhesion, migration and differentiation. This is one of the isozymes catalyzing that reaction (By similarity). [UniProt]
细胞定位	Membrane; Multi-pass membrane protein. [UniProt]
预测分子量	63 kDa

检测图片 (1) Click the Picture to Zoom In