ARG10785

anti-Guanylate Cyclase C antibody

anti-Guanylate Cyclase C antibody for Confocal microscopy (Confocal),Dot blot,ELISA,ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat

概述

产品描述 Rabbit Polyclonal antibody recognizes Guanylate Cyclase C
反应物种 Hu, Ms, Rat
应用 Confocal, Dot, ELISA, ICC/IF, IHC-P, WB
宿主 Rabbit
克隆 Polyclonal
同位型 IgG
靶点名称 Guanylate Cyclase C
抗原物种 Rat
抗原 Synthetic peptide around the C-terminus from Rat Guanylyl cyclase C.
偶联标记 Un-conjugated
別名 MECIL; STAR; STA receptor; MUCIL; hSTAR; Heat-stable enterotoxin receptor; Intestinal guanylate cyclase; Guanylyl cyclase C; GUC2C; EC 4.6.1.2; DIAR6; GC-C

应用说明

应用建议
应用 推荐稀释比
Confocal1:200
Dot1:10000
ELISA1:10000
ICC/IF1:200
IHC-P1:200
WB1:500
应用说明 * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

属性

形式 Liquid
纯化 Affinity purified.
缓冲液 Tris-Glycine Buffer (pH 7.4 - 7.8), Hepes, 0.02% Sodium azide, 30% Glycerol and 0.5% BSA.
抗菌剂 0.02% Sodium azide
稳定剂 30% Glycerol and 0.5% BSA
浓度 0.65 mg/ml
存放说明 For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项 For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接

GeneID: 14917 Mouse GUCY2C

GeneID: 2984 Human GUCY2C

Swiss-port # P25092 Human Heat-stable enterotoxin receptor

Swiss-port # Q3UWA6 Mouse Heat-stable enterotoxin receptor

基因名称 Gucy2c
全名 guanylate cyclase 2C
生物功能 Receptor for the E.coli heat-stable enterotoxin (E.coli enterotoxin markedly stimulates the accumulation of cGMP in mammalian cells expressing GC-C). Also activated by the endogenous peptides guanylin and uroguanylin. [UniProt]
预测分子量 123 kDa
翻译后修饰 Glycosylation at Asn-75 and/or Asn-79 is required for interaction with VIP36 while glycosylation at Asn-345 and Asn-402 modulates ligand-mediated GC-C activation.

检测图片 (2) Click the Picture to Zoom In

  • ARG10785 anti-Guanylate Cyclase C antibody IHC image

    Immunohistochemistry: Thin section of Mouse small intestine stained with ARG10785 anti-Guanylate Cyclase C antibody (red). Blue: Nuclei.

  • ARG10785 anti-Guanylate Cyclase C antibody WB image

    Western blot: Recombinant Guanylyl cyclase C protein stained with ARG10785 anti-Guanylate Cyclase C antibody at 1:500 dilution.