ARG62497
anti-Glycophorin C antibody [Ret40f]
anti-Glycophorin C antibody [Ret40f] for IHC-Frozen sections,IHC-Formalin-fixed paraffin-embedded sections and Human
Cell Biology and Cellular Response antibody
概述
| 产品描述 | Mouse Monoclonal antibody [Ret40f] recognizes Glycophorin C |
|---|---|
| 反应物种 | Hu |
| 应用 | IHC-Fr, IHC-P |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 克隆号 | Ret40f |
| 同位型 | IgG1, kappa |
| 靶点名称 | Glycophorin C |
| 抗原 | Red cell ghosts |
| 偶联标记 | Un-conjugated |
| 別名 | Glycophorin-D; CD236R; GPD; Glycophorin-C; Glycoprotein beta; Glycoconnectin; GPC; PAS-2; CD antigen CD236; GE; CD236; Sialoglycoprotein D; GYPD; PAS-2' |
应用说明
| 应用建议 |
|
||||||
|---|---|---|---|---|---|---|---|
| 应用说明 | IHC-P: Antigen Retrieval: Heat tissue section in Sodium citrate buffer (pH 6.0) or EDTA buffer (pH 8.0) IHC-Fr: Incubate for 30-60 minutes at room temperature is highly recommended. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 缓冲液 | 1X PBS buffer with < 0.1% sodium azide. |
| 抗菌剂 | < 0.1% sodium azide. |
| 浓度 | 2 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | GYPC |
| 全名 | glycophorin C (Gerbich blood group) |
| 背景介绍 | Glycophorin C (GYPC) is an integral membrane glycoprotein. It is a minor species carried by human erythrocytes, but plays an important role in regulating the mechanical stability of red cells. A number of glycophorin C mutations have been described. The Gerbich and Yus phenotypes are due to deletion of exon 3 and 2, respectively. The Webb and Duch antigens, also known as glycophorin D, result from single point mutations of the glycophorin C gene. The glycophorin C protein has very little homology with glycophorins A and B. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Feb 2012] |
| 生物功能 | This protein is a minor sialoglycoprotein in human erythrocyte membranes. The blood group Gerbich antigens and receptors for Plasmodium falciparum merozoites are most likely located within the extracellular domain. Glycophorin-C plays an important role in regulating the stability of red cells. [UniProt] |
| 细胞定位 | Cell membrane |
| 研究领域 | Cell Biology and Cellular Response antibody |
| 预测分子量 | 14 kDa |
| 翻译后修饰 | O-glycosylated with core 1 or possibly core 8 glycans. |
