ARG43594
anti-Glutathione Reductase antibody
anti-Glutathione Reductase antibody for Flow cytometry,ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes Glutathione Reductase |
|---|---|
| 反应物种 | Hu |
| 应用 | FACS, ICC/IF, IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | Glutathione Reductase |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide within a.a. 380-408 from the C-terminal region of human Glutathione Reductase. |
| 偶联标记 | Un-conjugated |
| Protein Full name | Glutathione reductase, mitochondrial |
| 別名 | GRase; HEL-75; EC 1.8.1.7; Glutathione reductase, mitochondrial; GR |
应用说明
| 应用建议 |
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| 应用说明 | IHC-P: Antigen Retrieval: Heat mediation antigen retrieval is needed. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
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| 实际分子量 | ~ 55 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purification with Protein A and immunogen peptide. |
| 缓冲液 | PBS and 0.09% (W/V) Sodium azide. |
| 抗菌剂 | 0.09% (W/V) Sodium azide |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # P00390 Human Glutathione reductase, mitochondrial |
|---|---|
| 基因名称 | GSR |
| 全名 | glutathione reductase |
| 背景介绍 | This gene encodes a member of the class-I pyridine nucleotide-disulfide oxidoreductase family. This enzyme is a homodimeric flavoprotein. It is a central enzyme of cellular antioxidant defense, and reduces oxidized glutathione disulfide (GSSG) to the sulfhydryl form GSH, which is an important cellular antioxidant. Rare mutations in this gene result in hereditary glutathione reductase deficiency. Multiple alternatively spliced transcript variants encoding different isoforms have been found. [provided by RefSeq, Aug 2010] |
| 生物功能 | Maintains high levels of reduced glutathione in the cytosol. [UniProt] |
| 细胞定位 | Cytoplasm, Mitochondrion |
| 预测分子量 | 56 kDa |
| 翻译后修饰 | Acetylation, Disulfide bond |
