概述

产品描述	Rabbit Polyclonal antibody recognizes Gephyrin
反应物种	Hu, Rat
应用	WB
宿主	Rabbit
克隆	Polyclonal
同位型	IgG
靶点名称	Gephyrin
抗原物种	Rat
抗原	Synthetic peptide
偶联标记	Un-conjugated
別名	GPHN; Gephyrin; KIAA1385; GPH; GEPH; GPHRYN; MOCODC; HKPX1

应用说明

应用建议	应用 推荐稀释比 WB 1:1000
应用说明	* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

属性

形式	Liquid
纯化	Antigen Affinity Purified
缓冲液	10 mM HEPES (pH 7.5), 150 mM NaCl, 50% Glycerol and 100 µg/ml BSA.
稳定剂	50% Glycerol and 100 µg/ml BSA
存放说明	For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项	For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接	GeneID: 10243 Human GPHN GeneID: 64845 Rat GPHN Swiss-port # Q03555 Rat Gephyrin Swiss-port # Q9NQX3 Human Gephyrin
基因名称	GPHN
全名	Gephyrin
背景介绍	This gene encodes a neuronal assembly protein that anchors inhibitory neurotransmitter receptors to the postsynaptic cytoskeleton via high affinity binding to a receptor subunit domain and tubulin dimers. In nonneuronal tissues, the encoded protein is also required for molybdenum cofactor biosynthesis. Mutations in this gene may be associated with the neurological condition hyperplexia and also lead to molybdenum cofactor deficiency. Numerous alternatively spliced transcript variants encoding different isoforms have been described; however, the full-length nature of all transcript variants is not currently known.
生物功能	Microtubule-associated protein involved in membrane protein-cytoskeleton interactions. It is thought to anchor the inhibitory glycine receptor (GLYR) to subsynaptic microtubules.
细胞定位	Cell membrane, Cell projection, Cytoplasm, Cytoskeleton, Membrane, Postsynaptic cell membrane, Synapse
预测分子量	83 kDa
翻译后修饰	Lipoprotein, Palmitate, Phosphoprotein

检测图片 (1) Click the Picture to Zoom In