ARG59639
anti-GUSB / beta glucuronidase antibody
anti-GUSB / beta glucuronidase antibody for Flow cytometry,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes GUSB / beta glucuronidase |
|---|---|
| 反应物种 | Hu |
| 预测物种 | Pig |
| 应用 | FACS, IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | GUSB / beta glucuronidase |
| 抗原物种 | Human |
| 抗原 | KLH-conjugated synthetic peptide corresponding to aa. 335-362 of Human GUSB. |
| 偶联标记 | Un-conjugated |
| 別名 | Beta-G1; MPS7; BG; EC 3.2.1.31; Beta-glucuronidase |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| 阳性对照 | K562 |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purification with Protein A and immunogen peptide. |
| 缓冲液 | PBS and 0.09% (W/V) Sodium azide. |
| 抗菌剂 | 0.09% (W/V) Sodium azide |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | GUSB |
| 全名 | glucuronidase, beta |
| 背景介绍 | This gene encodes a hydrolase that degrades glycosaminoglycans, including heparan sulfate, dermatan sulfate, and chondroitin-4,6-sulfate. The enzyme forms a homotetramer that is localized to the lysosome. Mutations in this gene result in mucopolysaccharidosis type VII. Alternative splicing results in multiple transcript variants. There are many pseudogenes of this locus in the human genome.[provided by RefSeq, May 2014] |
| 生物功能 | Plays an important role in the degradation of dermatan and keratan sulfates. [UniProt] |
| 细胞定位 | Lysosome. [UniProt] |
| 预测分子量 | 75 kDa |
| 翻译后修饰 | N-linked glycosylated with 3 to 4 oligosaccharide chains. [UniProt] |
检测图片 (3) Click the Picture to Zoom In
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ARG59639 anti-GUSB / beta glucuronidase antibody IHC-P image
Immunohistochemistry: Formalin-fixed and paraffin-embedded Human colon carcinoma stained with ARG59639 anti-GUSB / beta glucuronidase antibody.
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ARG59639 anti-GUSB / beta glucuronidase antibody WB image
Western blot: 35 µg of K562 cell lysate stained with ARG59639 anti-GUSB / beta glucuronidase antibody.
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ARG59639 anti-GUSB / beta glucuronidase antibody FACS image
Flow Cytometry: WiDr cells stained with ARG59639 anti-GUSB / beta glucuronidase antibody (right histogram) or without primary antibody as control (left histogram), followed by incubation with FITC labelled secondary antibody.
