ARG59606
anti-GUCY2F antibody
anti-GUCY2F antibody for Western blot and Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes GUCY2F |
|---|---|
| 反应物种 | Ms, Rat |
| 应用 | WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | GUCY2F |
| 抗原物种 | Human |
| 抗原 | Recombinant fusion protein corresponding to aa. 250-460 of Human GUCY2F (NP_001513.2). |
| 偶联标记 | Un-conjugated |
| 別名 | ROS-GC2; CYGF; Rod outer segment membrane guanylate cyclase 2; Guanylate cyclase F; Retinal guanylyl cyclase 2; GC-F; GUC2F; GUC2DL; EC 4.6.1.2; RETGC-2; Guanylate cyclase 2F, retinal |
应用说明
| 应用建议 |
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|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| 阳性对照 | Mouse eye | ||||
| 实际分子量 | 125 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified. |
| 缓冲液 | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 50% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | GUCY2F |
| 全名 | guanylate cyclase 2F, retinal |
| 背景介绍 | The protein encoded by this gene is a guanylyl cyclase found predominantly in photoreceptors in the retina. The encoded protein is thought to be involved in resynthesis of cGMP after light activation of the visual signal transduction cascade, allowing a return to the dark state. This protein is a single-pass type I membrane protein. Defects in this gene may be a cause of X-linked retinitis pigmentosa. [provided by RefSeq, Dec 2008] |
| 生物功能 | Probably plays a specific functional role in the rods and/or cones of photoreceptors. It may be the enzyme involved in the resynthesis of cGMP required for recovery of the dark state after phototransduction. [UniProt] |
| 细胞定位 | Membrane; Single-pass type I membrane protein. [UniProt] |
| 预测分子量 | 125 kDa |
| 翻译后修饰 | There are 9 conserved cysteine residues in sensory guanylate cyclases, 6 in the extracellular domain, which may be involved in intra- or interchain disulfide bonds. [UniProt] |
检测图片 (1) Click the Picture to Zoom In
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ARG59606 anti-GUCY2F antibody WB image
Western blot: 25 µg of Mouse eye lysate stained with ARG59606 anti-GUCY2F antibody at 1:1000 dilution.
