ARG55722
anti-GTSE1 antibody
anti-GTSE1 antibody for Flow cytometry,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes GTSE1 |
|---|---|
| 反应物种 | Hu |
| 应用 | FACS, IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | GTSE1 |
| 抗原物种 | Human |
| 抗原 | KLH-conjugated synthetic peptide corresponding to aa. 690-717 (C-terminus) of Human GTSE1. |
| 偶联标记 | Un-conjugated |
| 別名 | GTSE-1; G2 and S phase-expressed protein 1; Protein B99 homolog; B99 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| 阳性对照 | MCF7 |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purification with Protein A and immunogen peptide |
| 缓冲液 | PBS and 0.09% (W/V) Sodium azide |
| 抗菌剂 | 0.09% (W/V) Sodium azide |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # Q9NYZ3 Human G2 and S phase-expressed protein 1 |
|---|---|
| 基因名称 | GTSE1 |
| 全名 | G-2 and S-phase expressed 1 |
| 背景介绍 | The protein encoded by this gene is only expressed in the S and G2 phases of the cell cycle, where it colocalizes with cytoplasmic tubulin and microtubules. In response to DNA damage, the encoded protein accumulates in the nucleus and binds the tumor suppressor protein p53, shuttling it out of the nucleus and repressing its ability to induce apoptosis. [provided by RefSeq, Jul 2008] |
| 生物功能 | May be involved in p53-induced cell cycle arrest in G2/M phase by interfering with microtubule rearrangements that are required to enter mitosis. Overexpression delays G2/M phase progression. [UniProt] |
| 预测分子量 | 77 kDa |
| 翻译后修饰 | Phosphorylated in mitosis. |
检测图片 (3) Click the Picture to Zoom In
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ARG55722 anti-GTSE1 antibody IHC-P image
Immunohistochemistry: Formalin-fixed and paraffin-embedded brain tissue stained with ARG55722 anti-GTSE1 antibody.
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ARG55722 anti-GTSE1 antibody WB image
Western blot: 20 µg of MCF7 whole cell lysate stained with ARG55722 anti-GTSE1 antibody at 1:1000 dilution.
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ARG55722 anti-GTSE1 antibody FACS image
Flow Cytometry: HeLa cells stained with ARG55722 anti-GTSE1 antibody (right histogram) or without primary antibody as control (left histogram), followed by incubation with FITC labelled secondary antibody.
